Results 71 to 80 of about 22,612 (260)

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

To the history of the method of transosseous osteosynthesis in the Middle Urals

Гений oртопедии, 2021
Background The article reviews the history of the study, development and application of the method of transosseous osteosynthesis in the Middle Urals. G.A. Ilizarov first presented his device and the results of its use in fracture repair at a meeting of
Sergei M. Kutepov, Stella V. Gulnazarova
doaj   +1 more source

From plan to market : patterns of transition [PDF]

In analyzing the transitional experience of countries in Central and Eastern Europe (CEE) and the former Soviet Union (FSU), the authors find strong common patterns for countries at similar stages of reform despite differences in initial conditions.
Denizer, Cevdet, Gelb, Alan, de Melo, Martha   +2 more
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Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

FEATURES OF THE GENERAL-GOVERNOR’S AUTHORITY IN SIBERIA IN THE FIRST HALF OF THE XIX CENTURY

Вестник Кемеровского государственного университета, 2017
On the basis of pre-revolutionary legislation, the article comprehensively considers features of general-governor’s power. The article also analyzes the system of Siberian administration in the first half of XIX century.
Igor A. Konovalov
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

The formless empire : the evolution of indigenous Eurasian geopolitics

, 2014
This dissertation seeks to make a unique contribution to the study of geopolitics and empire in Central Asia by focusing on both the indigenous developments of grand strategies and their legacies by examining several key points in the history of the ...
Mott, Christopher Douglas
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Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Empirical tests of the Marshall–Lerner condition: evidence from Egypt–BRICS commodity trade using ARDL approach

Future Business Journal
This study seeks to test the validity of the Marshall–Lerner (M-L) condition between Egypt and BRICS countries (five countries: Brazil, Russia, India, China, and South Africa) to determine which industries will benefit from depreciation in the long run ...
Hebatallah Ahmed Soliman
doaj   +1 more source

Is the European Court of Human Rights satisfied with the Russian criminal justice system? [PDF]

, 2007
This article considers the extent to which the Russian criminal justice system complies with human rights standards. About a third of the complaints against Russia that are filed at the European Court of Human Rights (ECtHR) relate to violations of ...
Voskobitova, Maria R.
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