打鼾与卒中相关性Meta分析 A Meta-analysis on the Correlation between Snoring and Stroke
目的 系统评价打鼾合并卒中的风险。 方法 计算机检索PubMed、Web of Science、中国知网、万方等数据库,手工检索打鼾与卒中的病例对照研究、队列研究及横断面研究的原始研究文献,检索时限为建库至2018年10月1日。采用Stata 15.0软件进行Meta分析、亚组分析及敏感性分析和发表偏倚分析。 结果 共纳入文献11篇,包括研究对象235 920例,卒中患者2681例。无明显发表偏倚。研究整体间无明显异质性,采用固定效应模型进行合并,结果显示,打鼾人群发生卒中的风险更高(OR 1 ...
刘师垚,周洲洋,吉诗雨,石冰
doaj +1 more source
American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non–Small-Cell Lung Cancer [PDF]
The purpose of this article is to provide updated recommendations for the treatment of patients with stage IV non-small-cell lung cancer. A literature search identified relevant randomized trials published since 2002.
AZZOLI, Christopher G +21 more
core +1 more source
Electroconvulsive therapy for agitation in schizophrenia: Meta-analysis of randomized controlled trials [PDF]
Background: Agitation poses a significant challenge in the treatment of schizophrenia. Electroconvulsive therapy (ECT) is a fast, effective and safe treatment for a variety of psychiatric disorders, but no meta-analysis of ECT treatment for agitation in ...
Cao, Xiaolan +9 more
core +1 more source
Abstract Active outdoor play has been positioned in the literature as an opportunity to address concerns over climate (in)action and the rising trend of disconnection from the outdoors and nature. The objective of this systematic review was to examine associations between active outdoor play and people's connection to nature and/or environmental ...
Louise de Lannoy +10 more
wiley +1 more source
目的 构建GWAS标准化流程及多组学分析体系框架,为基于多组学队列的脑血管病药物逆向研发提供高效分析方法。 方法 基于国际GWAS质量控制标准与多组学整合与分析策略,构建模块化的分析体系。GWAS前数据质量控制模块:对样本和变异检出率、群体遗传结构与分层、亲缘关系等进行严格质量控制。在合格样本组成的群体中,保留次要等位基因频率>0.5%的遗传变异用于GWAS。关联分析模块:利用PLINK、SAIGE和Regenie等软件,使用广义线性模型与广义线性混合模型进行GWAS操作。通过基因组膨胀系数和分位数-
许喆1,2,石延枫1,2,张杰1,2,姜明慧1,2,刘阳1,2,李昊1,2,3,廖晓凌4,程丝1,2,3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)
doaj +1 more source
A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
core
Meta-analysis of relationship between short-term ozone exposure and population mortality in China [PDF]
BackgroundIn recent years, our country's atmospheric particulate matter pollution has improved significantly, while ozone (O3) pollution has become increasingly serious. As a secondary pollutant, O3 is closely related to human health.
Haiping TAN +4 more
core +2 more sources
This population‐comparative study reveals that male and female parents respond differently to social and ecological conditions. This sex‐specific responsive strategy is related to the incongruent parental care systems across populations in Chinese penduline tits.
Jia Zheng +5 more
wiley +1 more source
A Systematic Review on Different Treatment Methods of Bone Metastasis from Cancers [PDF]
Background and objective Skeletal metastase is one of the most common complications related to advanced cancer. The aim of this study is to analyze the effectiveness and safety of radiotherapy plus intravenous bisphosphonates versus radiotherapy alone ...
Jinhui TIAN +4 more
core
Evaluating synthetic substitutes to reduce illegal harvesting and support species recovery
Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened species. Yet, there is little evidence on whether product substitution prevents illegal or unsustainable harvesting and contributes to the recovery of threatened populations.
Aditya Shekhar Malgaonkar +17 more
wiley +1 more source

