Results 101 to 110 of about 17,999 (266)

Computational Intelligence Accelerates CRISPR‐Cas‐Based Diagnostic Design

iLABMED, EarlyView.
Computational intelligence, including pangenome‐guided target mining, machine‐learning‐based guide RNA optimization, and autonomous AI agents, is shifting CRISPR diagnostic design from empirical screening to systematic, data‐driven engineering and accelerating the path from pathogen discovery to deployable diagnostics.
Hengyu Wang, Qiurun He, Xuhu Mao, Yong Sheng   +3 more
wiley   +1 more source

Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes

iMeta, EarlyView.
Nanopore direct RNA sequencing advances transcriptomics by capturing full‐length transcripts and multiple RNA modifications; this review details its principles, workflows, tools, applications, challenges, and future research potential. Abstract Nanopore direct RNA sequencing (DRS) has transformed transcriptomics by enabling single‐molecule, long‐read ...
Tianyuan Zhang, Jia Li, Chao Tang, You Wu, Hao Wu, Xi‐Tong Zhu, Ziyang Luo, Hang Qin, Lishan Ding, Yu Zeng, Shiou Yih Lee, Xiaotao Shen, Shiwen Gao, Zhaoyang Tian, Qian Tang, Mian Li, Muhammad Tahir Ul Qamar, Yang Dong, Komivi Dossa, Yaxuan Zhang, Hu Chen, Sanqi An, Xiang Yu, Lu Chen, Dingjie Wang, Shengli Li, Ling‐Ling Chen, Yanqiang Li   +27 more
wiley   +1 more source

Medical Reasoning With Large Language Models: A Systematic Review and Evaluation

iNew Medicine, EarlyView.
ABSTRACT Large language models (LLMs) have achieved strong performance on medical exam–style tasks, motivating growing interest in their deployment in real‐world clinical settings. However, clinical decision‐making is inherently safety‐critical, context‐dependent, and conducted under evolving evidence.
Xiaohan Ren, Chenxiao Fan, Wenyin Ma, Hongliang He, Chongming Gao, Xiaoyan Zhao, Fuli Feng   +6 more
wiley   +1 more source

IHML: Incremental Heuristic Meta-Learner

Applied Artificial Intelligence
The landscape of machine learning constantly demands innovative approaches to enhance algorithms’ performance across diverse tasks. Meta-learning, known as “learning to learn” is a promising way to overcome these diversity challenges by blending multiple
Onur Karadeli, Kıymet Kaya, Şule Gündüz Öğüdücü   +2 more
doaj   +1 more source

Do Linking‐Expression Substitutions Mitigate Deterministic Interpretations of Genetic Information?

Journal of Applied Philosophy, EarlyView.
ABSTRACT It is a common concern that broader audiences interpret scientific information about the genetic correlates and causes of complex human traits in an overly deterministic manner. A frequently proposed way to address this issue is to carefully select the linking expressions used to describe gene–trait relationships when communicating genetic ...
Riin Kõiv
wiley   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

JCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan, Robbie Duschinsky, Marian J. Bakermans‐Kranenburg, Lianne Bakkum, Guy C. M. Skinner, Alfred Markham, Helen Beckwith, Marinus H. van Ijzendoorn   +7 more
wiley   +1 more source

Toward an idiographic understanding of the role of sleep‐mood dynamics in adolescents' internalizing symptoms

JCPP Advances, EarlyView.
Abstract Background Adolescence is marked by increased vulnerability to sleep disturbances and mood disorders. Understanding how day‐to‐day changes in sleep and mood are linked within the same individual is crucial for clarifying sleep's role in emerging internalizing disorders. However, the extent to which an adolescent's fluctuations in sleep predict
Konstantin Drexl, Setareh Ranjbar, Sébastien Urben, Kerstin Jessica Plessen, Jennifer Glaus   +4 more
wiley   +1 more source

News dissemination prediction based on meta heuristic optimization fuzzy algorithm

Discover Computing
The rapid growth of online platforms and social media has significantly changed how news is disseminated, creating challenges in predicting its reach and impact due to dynamic user behavior and unstructured information flow.
Dandan Zhao
doaj   +1 more source

Meshless Search SR-STAP for Airborne Radar Based on Meta-Heuristic Algorithms. [PDF]

Sensors (Basel), 2023
Hou Y, Zhang Y, Gui W, Wang D, Dong W.
europepmc   +1 more source

When Does Top Management Team Diversity Matter in Large Organizations?

Journal of Organizational Behavior, EarlyView.
ABSTRACT Top management teams (TMTs) drive strategic leadership, but there is little clarity on when the composition of these upper echelons most impacts organization performance. Drawing from the categorization‐elaboration model, we study an 18‐year sample of approximately 4500 organizations and over 32 000 executives and find a positive relationship ...
Frances Fabian, James M. Plečnik, Shan Wang   +2 more
wiley   +1 more source