Results 41 to 50 of about 1,434,275 (265)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Meta-SQL: Towards Practical Meta-Querying [PDF]
, 2004 Enterprise databases often contain not only ordinary data, but also queries. Examples are view definitions in the system catalog; usage logs or workloads; and stored procedures as in SQL/PSM or Postgres. Unfortunately, these queries are typically stored as long strings, which makes it hard to use standard SQL to express meta-queries: queries about ...
Jan Van den Bussche +2 more
openaire +4 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Striving toward ecological validity in hearing science: evaluating a variety of hearing assessments
Frontiers in Audiology and OtologyObjectiveTraditional audiological assessments, such as the audiogram, often fail to capture the complexity of real-world hearing experiences. This study aims to determine whether hearing assessments that incorporate key real-world factors: the presence ...
Liesbeth Gijbels +4 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics
Advanced ScienceWearable electronics are essential for health monitoring, haptic feedback, and human‐computer interaction. However, maintaining stable contact with skin remains challenging due to its softness, roughness, and variability across body sites.
Seola Lee +10 more
doaj +1 more source
Electromagnetic metamaterials for biomedical applications: short review and trends
EPJ Applied MetamaterialsThis mini-review examines the most prominent features and usages of metamaterials, such as metamaterial-based and metamaterial-inspired RF components used for biomedical applications.
Tzarouchis Dimitrios C. +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source