Results 71 to 80 of about 2,476,881 (313)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Evolución del Programa de Control de Tuberculosis en el Servicio Seccional de Salud del Meta
Medicina, 1990 <p><em><strong>La Academia Nacional de Medicina y el Ministerio de Salud patrocinaron en la sede de nuestra Corporación, un Seminario Coordinado por el académico doctor Gilberto Rueda Pérez, para estudiar el estado actual de la Campana
Pedro Pablo Velásquez Rico +5 more
doaj
Frontiers in PharmacologyBackgroundTraditional botanical drugs and medicinal plants, along with their metabolite extracts, have exhibited considerable potential in the management of knee osteoarthritis (KOA) due to their natural properties, favorable safety profiles, and minimal
Chao Yan +7 more
doaj +1 more source
, 2022 Actualizar el sistema de gestión de seguridad y salud en el trabajo, enfocados hacia la mejora continua de los procesos de la Corporación Universitaria Del Meta - UNIMETA.1 Introducción......................................................................
Torres Rey, Camila Alejandra
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Informe final de práctica empresarial: Asociación de Periodistas y Comunicadores del Meta - ASOPEMET
, 2022 Proporcionar una alternativa de libre expresión enfocada en la creación de contenidos. Generar una adaptabilidad del público juvenil a la Asociación de Periodistas y Comunicadores del Meta.
Pardo Granados, Andrés Guillermo
core
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Aging and Cancer, EarlyView.In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source