Results 241 to 250 of about 3,290,125 (315)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Behavioral-metabolic phenotypes and differential risks of diabetic kidney disease and peripheral neuropathy in type 2 diabetes: a latent class analysis. [PDF]

Front Endocrinol (Lausanne)
Wang Y, Liu Z, Zhang Z, Hu A, Liu L, Zeng S, Liu P, Wang Y, Sun L.   +8 more
europepmc   +1 more source

Living Well, Living Longer: Working together for better health in people with mental illness

International Journal of Integrated Care, 2014
Liesl Duffy, Andrew McDonald, Tim Lambert, Sue Sacker, Michael Moore, Ian Caterson, Jeff Snars, Len Kritharides, Victor Storm, Paul Clenaghan, Janice Purvis, Sameer Bhole, Phil Escott, Angela Meaney, Robert Lusby, Ron Grunstein, Lou-Anne Blunden, Clair Edwards, Deborah Willcox, Tim Sinclair, Madeleine Kitchener, Karen Bedford, Paul Haber, Simon Cowap, Rose Meiruntu, Stephen Simpson, Nick Glozier, Leena Gupta, Teresa Anderson   +28 more
doaj  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Metabolic Milieu and Susceptibility: The Combined Benefits of Targeting AMPK and ACE2 for Metabolic Disorders and COVID-19. [PDF]

Int J Mol Sci
Tata FY, Nxumalo MB, Ntanzi N, Mushebenge AG, Khan RB, Kumalo HM.   +5 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Editorial: Immunometabolism at the intersection of signaling networks and therapeutic strategies. [PDF]

Front Immunol
Damasceno LEA, Toller-Kawahisa JE.
europepmc   +1 more source