Results 271 to 280 of about 3,290,125 (315)
Some of the next articles are maybe not open access.
Journal of Nephrology, 2001
Abstract: Metabolic alkalosis is a primary pathophysiologic event characterized by the gain of bicarbonate or the loss of nonvolatile acid from extracellular fluid. The kidney preserves normal acid-base balance by two mechanisms: bicarbonate reclamation mainly in the proximal tubule and bicarbonate generation predominantly in the ...
A, Khanna, N A, Kurtzman
openaire +3 more sources
Abstract: Metabolic alkalosis is a primary pathophysiologic event characterized by the gain of bicarbonate or the loss of nonvolatile acid from extracellular fluid. The kidney preserves normal acid-base balance by two mechanisms: bicarbonate reclamation mainly in the proximal tubule and bicarbonate generation predominantly in the ...
A, Khanna, N A, Kurtzman
openaire +3 more sources
Clinics in Liver Disease, 1998
Most tissues of the body contain enzymes capable of ethanol oxidation or nonoxidative metabolism, but significant activity occurs only in the liver and, to a lesser extent, in the stomach. Hence, medical consequences are predominant in these organs. In the liver, ethanol oxidation generates an excess of reducing equivalents, primarily as NADH, causing ...
openaire +2 more sources
Most tissues of the body contain enzymes capable of ethanol oxidation or nonoxidative metabolism, but significant activity occurs only in the liver and, to a lesser extent, in the stomach. Hence, medical consequences are predominant in these organs. In the liver, ethanol oxidation generates an excess of reducing equivalents, primarily as NADH, causing ...
openaire +2 more sources
Pediatrics, 1956
IT IS the part of wisdom when about to give a dissertation which one hopes will at once instruct and entertain, to provide at the outset some definition of the subject matter. Genetics is the study of the heritable components of variation; the heritable factors which determine the range or extent of diversity.
openaire +2 more sources
IT IS the part of wisdom when about to give a dissertation which one hopes will at once instruct and entertain, to provide at the outset some definition of the subject matter. Genetics is the study of the heritable components of variation; the heritable factors which determine the range or extent of diversity.
openaire +2 more sources
Current Rheumatology Reports, 2010
We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
openaire +2 more sources
We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
openaire +2 more sources
Applied Microbiology and Biotechnology, 2001
Metabolic engineering has developed as a very powerful approach to optimising industrial fermentation processes through the introduction of directed genetic changes using recombinant DNA technology. Successful metabolic engineering starts with a careful analysis of cellular function; based on the results of this analysis, an improved strain is designed
openaire +2 more sources
Metabolic engineering has developed as a very powerful approach to optimising industrial fermentation processes through the introduction of directed genetic changes using recombinant DNA technology. Successful metabolic engineering starts with a careful analysis of cellular function; based on the results of this analysis, an improved strain is designed
openaire +2 more sources
Seminars in Pediatric Neurology, 1996
Disorders of glycogen, lipid or mitochondrial metabolism may cause two main clinical syndromes, namely (1) progressive weakness (eg, acid maltase, debrancher enzyme, and brancher enzyme deficiencies among the glycogenoses; long- and very-long-chain acyl-CoA dehydrogenase (LCAD, VLCAD), and trifunctional enzyme deficiencies among the fatty acid ...
openaire +2 more sources
Disorders of glycogen, lipid or mitochondrial metabolism may cause two main clinical syndromes, namely (1) progressive weakness (eg, acid maltase, debrancher enzyme, and brancher enzyme deficiencies among the glycogenoses; long- and very-long-chain acyl-CoA dehydrogenase (LCAD, VLCAD), and trifunctional enzyme deficiencies among the fatty acid ...
openaire +2 more sources
Metabolism and Metabolic Regulation
2010The data available on GHR−/− at all ages. Glucose levels, which are very low in young animals, seem to normalize at older ages. Insulin levels remain significantly lower than normal throughout the lifespan of GHR−/− mice. Together, these data suggest that insulin sensitivity decreases only slightly as GHR−/− mice age.
Lucila Sackmann-Sala +2 more
openaire +1 more source
Inborn Errors of Metabolism (Metabolic Disorders)
Pediatrics in Review, 2016By their very nature, rare inborn errors of metabolism challenge the generation and application of evidence-based medicine. • On the basis of limited research evidence as well as consensus, newborn screening for select metabolic disorders, including phenylketonuria, medium-chain acyl CoA dehydrogenase deficiency, and glutaric acidemia type I, may ...
Gregory M, Rice, Robert D, Steiner
openaire +2 more sources
Fluoroacetylcarnitine: Metabolism and metabolic effects in mitochondria
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973Abstract The metabolism and metabolic effects of fluoroacetylcarnitine have been investigated. 1. 1. Carnitineacetyltransferase (EC 2.3.1.7) transfers the fluoro-acetyl group of fluoroacetylcarnitine nearly as rapidly to CoA as the acetyl group of acetylcarnitine. 2. 2. Fluorocitrate is then formed by citrate synthase (EC. 4.1.3.7.), but this
J, Bremer, E J, Davis
openaire +2 more sources
Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK
2016This chapter summarizes AMPK function in the regulation of substrate and energy metabolism with the main emphasis on carbohydrate and lipid metabolism, protein turnover, mitochondrial biogenesis, and whole-body energy homeostasis. AMPK acts as whole-body energy sensor and integrates different signaling pathway to meet both cellular and body energy ...
Yeliz, Angin +3 more
openaire +2 more sources