Results 281 to 290 of about 1,343,805 (370)

The Landscape of Cancer Metabolism as a Therapeutic Target

open access: yesPathology International, EarlyView.
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley   +1 more source

The impact of pressure and temperature on the quality of suspended red blood cells: An ex vivo simulation study

open access: yesTransfusion Medicine, EarlyView.
Abstract Objective This study aims to explore the impact of pressurisation and simultaneous warming at a combination of 50 kPa and 46°C on the quality of suspended red blood cells in an ex vivo environment. Background During massive rapid blood transfusion, pressure and temperature‐controlled blood warming devices are often used to prevent hypothermia ...
Chunyu Feng   +3 more
wiley   +1 more source

A.125 Effect of metabolic acidosis and its correction on myocardial performance of an isolated blood perfused rabbit heart

open access: bronze, 1996
Didier Sirieix   +4 more
openalex   +1 more source

Biochemical Reference Intervals of Free‐Ranging Koalas (Phascolarctos cinereus) in South Australia

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Reference intervals (RIs) are an essential tool for assessment of clinical pathology data of animals, and are particularly important for monitoring the health status of free‐ranging and captive wildlife, such as koalas (Phascolarctos cinereus). Objectives The purpose of this study was to: (1) provide comprehensive serum biochemistry
María B. Font   +9 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

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