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Topiramate and Metabolic Acidosis
Epilepsia, 1999Summary: Topiramate (TPM) is a novel antiepileptic medication (AED) with at least three mechanisms of action. A possible fourth mechanism, that of a carbonic anhydrase inhibitor, also may contribute to its antiepileptic properties. We report a patient with intractable epilepsy and normal renal function who developed a normal anion gap metabolic ...
Kent Raymond +2 more
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Adverse Effects of the Metabolic Acidosis of Chronic Kidney Disease.
Advances in Chronic Kidney Disease, 2017The kidney has the principal role in the maintenance of acid-base balance, and therefore, a fall in renal net acid excretion and positive H+ balance often leading to reduced serum [HCO3-] are observed in the course of CKD.
J. Kraut, N. Madias
semanticscholar +1 more source
Hyperchloraemic metabolic acidosis
Emergency Medicine Journal, 2008Cholestyramine carries a risk of hyperchloraemic metabolic acidosis. Being cognisant of this drug-induced adverse event may reduce diagnostic delays. Emergency physicians should be alert about this condition, in particular among patients with pre-existing chronic kidney disease, or who are taking spironolactone.
Florence Fan +3 more
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Veterinary Clinics of North America: Food Animal Practice, 1999
In neonatal calves metabolic acidosis is a common sequela to diarrhea-induced dehydration and endotoxemia in the aftermath of gram-negative bacterial infections. Without treatment, metabolic acidosis is a prime factor in the death of many of these calves.
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In neonatal calves metabolic acidosis is a common sequela to diarrhea-induced dehydration and endotoxemia in the aftermath of gram-negative bacterial infections. Without treatment, metabolic acidosis is a prime factor in the death of many of these calves.
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Phenformin-associated metabolic acidosis
Diabetes, 1976We report 18 consecutive phenformin-treated diabetic patients admitted to this Medical Service acutely ill with metabolic acidosis. Lactic acidosis was anticipated, and documented, in all. Also, however, though most of the patients had only weakly positive, or even negative, serum reactions with the nitroprusside reagent, all were found to have ...
Milford Fulop, Hemry D Hoberman
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Management of the Metabolic Acidosis of Chronic Kidney Disease.
Advances in Chronic Kidney Disease, 2017Subjects with CKD and reduced glomerular filtration rate are at risk for chronic metabolic acidosis, and CKD is its most common cause. Untreated metabolic acidosis, even in its mildest forms, is associated with increased mortality and morbidity and ...
Nimrit Goraya, D. Wesson
semanticscholar +1 more source
Hypophosphatemia and metabolic acidosis.
Minerva anestesiologica, 2005The aim of the paper was to describe an unusual case of non lactic metabolic acidosis connected to hypophosphatemia and refractory to infusion of bicarbonate. A 37 year old man was admitted to Intensive Care Unit with a severe metabolic acidosis. On admission the arterial gas analysis showed non lactic metabolic acidosis (pH 7.17; base excess [BE] -20 ...
PALMESE S, PEZZA M, DE ROBERTIS E
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Cardiovascular responses to metabolic acidosis
American Journal of Physiology-Legacy Content, 1965The performance of the left ventricle was examined in a feline preparation which allowed precise control of aortic pressure, cardiac output, heart rate, and temperature. The arterial pH, Po2, and Pco2 were continuously measured with a Jewett flow-through electrode assembly.
S. E. Downing +2 more
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Archives of Internal Medicine, 1965
METABOLIC ACIDOSIS is a clinical state characterized by an excess of hydrogen ions, the source of which are acids other than carbonic. In diabetic acidosis, the source of the excessive hydrogen ion is ketoacids formed during the process of intermediary metabolism in the absence of insulin. The degree of acidemia, ie, lowering of arterial blood pH, will
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METABOLIC ACIDOSIS is a clinical state characterized by an excess of hydrogen ions, the source of which are acids other than carbonic. In diabetic acidosis, the source of the excessive hydrogen ion is ketoacids formed during the process of intermediary metabolism in the absence of insulin. The degree of acidemia, ie, lowering of arterial blood pH, will
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Glutamine metabolism in metabolic acidosis.
Ciba Foundation symposium, 1982In chronic metabolic acidosis in the rat, there is increased ammoniagenesis, gluconeogenesis and renal extraction of glutamine with induction of renal phosphate-dependent glutaminase (PDG). Because the stimulus for these changes is not yet clear and also because acute acidosis is the more common clinical problem, the present study deals mainly with the
Jennifer Barnswell +6 more
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