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Hepatic targeting in ASCVD: integrating lipid lowering and inflammation modulation from statins to gene editing. [PDF]

J Transl Med
Xiao Q, Wang M, Wang S, Wang L, Ding H.
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Metabolic Clearance Rates of Diiodotyrosine in Man

The Journal of Clinical Endocrinology & Metabolism, 1972
In order to define the metabolic clearance rate (MCR) of diiodotyrosine (DIT) in normal subjects and to establish if there are alterations in clearance of DIT in patients with toxic Graves’ disease, MCR values of 125I-DIT were determined in eight normal subjects and five patients with thyrotoxicosis, utilizing a continuous infusion method. The MCR 125I-
P A, Singer, J T, Nicoloff
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Metabolic Clearance Rate and Urinary Clearance of Purified β-Core

The Journal of Clinical Endocrinology & Metabolism, 1989
We injected a highly purified preparation of the beta-core molecule, a fragment of hCG beta excreted in pregnancy urine, into five men and three women to determine its kinetic parameters, MCR, and urinary clearance. The beta-core molecule was distributed in an initial volume [1950 +/- 156 (mean +/- SEM) mL/m2 body surface area] approximately equal to ...
R E, Wehmann, D L, Blithe, M R, Flack, B C, Nisula   +3 more
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Metabolic clearance rate of adrenocorticotropin in the rat

Canadian Journal of Physiology and Pharmacology, 1977
The metabolic clearance rate (MCR) of adrenocorticotropin (ACTH) was estimated after the intravenous infusion of graded rates of the hormone (40–2560 μU/min per 100 g body weight) in rats pretreated with chlorpromazine, morphine, and Nembutal, a preparation which proved effective in blocking endogenous ACTH release.
J, Lalonde, M, Normand
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INCREASED STEROID METABOLIC CLEARANCE RATE IN ANEPHRIC PATIENTS

Acta Endocrinologica, 1974
ABSTRACT The control of plasma aldosterone level depends on the secretion rate and on the metabolic clearance rate (MCR) of the hormone. The rate of aldosterone metabolism was measured in 6 anephric patients in comparison with normal volunteers.
P, Corvol, X, Bertagna, J, Bedrossian
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