Results 181 to 190 of about 6,856,593 (214)

Can proton density-weighted MRI-based finite element models predict bone strength? [PDF]

Bone
Olowu BD, Auger JD, Morgan EF.
europepmc   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Modeling Release Scaffolds for Spinal Cord Tissue Regeneration After Injury Using COMSOL Simulation. [PDF]

Nanomaterials (Basel)
Al Dabbas TH, Bozeya A, Al Dabbas A.
europepmc   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Review of Breathable Electronics. [PDF]

Materials (Basel)
Fan J, Li J, Li S, Hong R, Ma J, Lei B, Dong P, Fan C, Xiao Q, Zhou J, Qiao Y.   +10 more
europepmc   +1 more source

Bioelectrochemically Powered Out‐of‐Equilibrium Hydrogels Enable Feedback‐Regulated Functions

Advanced Science, EarlyView.
A bioelectrochemically powered hydrogel operates far from equilibrium via an antagonistic redox cycle that regulates disulfide exchange within a polyrotaxane network. Coupling electrochemical mediator cycling with enzymatic feedback enables dynamic control of hydrogel mechanics and transport properties, driving glucose‐responsive insulin release with ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

Reprogramming product selectivity and activity in promiscuous terpene synthases via substrate conformation engineering. [PDF]

Nat Commun
Dong S, Liu H, Liao W, Chen X, Cui T, Zhang R, Wang Q, Han Y, Wang L, Men X, Zhang H.   +10 more
europepmc   +1 more source

A Single-Source Dual-Drive Flexible Knee Assistive Exoskeleton for Elderly Daily Locomotion. [PDF]

Cyborg Bionic Syst
Zhang S, Zhang Y, Xu Y, Li J, Leng Y, Wu X.   +5 more
europepmc   +1 more source

Stretchable large-area transparent nanowire composite arrays for label-free multimodal interrogation of cardiac physiology. [PDF]

Proc Natl Acad Sci U S A
Quirion NT, Alber BR, Dong C, Fehr A, Zhao Q, Shields N, Yang Z, Zhao H, Kay MW, Lu L.   +9 more
europepmc   +1 more source

Mapping the Prosthetic-Host Interactome: From Systemic Inflammation to Biological Integration in Mesh-Enhanced Therapies METs-A Scoping Review. [PDF]

Int J Mol Sci
Finascu FC, Oprea VC, Toma M, Bucuri CE, Molnar C, Finascu BA, Grigorescu BL, Suciu BA.   +7 more
europepmc   +1 more source