Metabolic engineering of human gut microbiome: Recent developments and future perspectives [PDF]
, 2023 Many studies have demonstrated that the gut microbiota is associated with human health and disease. Manipulation of the gut microbiota, e.g. supplementation of probiotics, has been suggested to be feasible, but subject to limited therapeutic efficacy. To
Roos, Stefan +11 more
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Engineering yeast for high-level production of diterpenoid sclareol [PDF]
, 2023 The diterpenoid sclareol is an industrially important precursor for alternative sustainable supply of ambergris. However, its current production from plant extraction is neither economical nor environmental-friendly, since it requires laborious and cost ...
Yu, Wei, +15 more
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Constraint-based metabolic control analysis for rational strain engineering [PDF]
, 2021 The advancements in genome editing techniques over the past years have rekindled interest in rational metabolic engineering strategies. While Metabolic Control Analysis (MCA) is a well-established method for quantifying the effects of metabolic ...
Ataman, Meriç +9 more
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Flow Feature Aligned Mesh Generation and Adaptation [PDF]
, 2013 Methods which allow for construction of flow feature aligned meshes in two- and three-dimensions have been developed in this thesis to investigate their potential for improvements in the numerical solution relative to globally refining the mesh.
Harris, Matthew
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Evolutionary multiobjective algorithms for in silico metabolic engineering [PDF]
, 2008 The aims of this Metabolic Engineering conference are to provide a forum for academic and industrial researchers in the field; to bring together the different scientific disciplines that contribute to the design, analysis and optimization of metabolic ...
Ferreira, Eugénio C. +5 more
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Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products [PDF]
, 2012 Zahoor ul Hassan A, Lindner S, Wendisch VF. Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products. Computational and Structural Biotechnology Journal.
Volker F. Wendisch +5 more
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Metabolic engineering under uncertainty. I: Framework development [PDF]
, 2006 Std. bioprocess conditions have been widely applied for the microbial conversion of raw material to essential industrial products. Successful metabolic engineering (ME) strategies require a comprehensive framework to manage the complexity embedded in ...
Hatzimanikatis, Vassily +3 more
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Single cell mutant selection for metabolic engineering of actinomycetes [PDF]
, 2022 Actinomycetes are important producers of pharmaceuticals and industrial enzymes. However, wild type strains require laborious development prior to industrial usage.
Fewer David P. +7 more
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Metabolic Engineering Optimizes Bioorthogonal Glycan Labeling in Living Cells [PDF]
, 2021 Metabolic oligosaccharide engineering (MOE) has fundamentally contributed to our understanding of protein glycosylation. Efficient MOE reagents are activated into nucleotide-sugars by cellular biosynthetic machineries, introduced into glycoproteins and ...
Junwon, Choi +13 more
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The future of metabolic engineering and synthetic biology: towards a systematic practice [PDF]
, 2012 Industrial biotechnology promises to revolutionize conventional chemical manufacturing in the years ahead, largely owing to the excellent progress in our ability to re-engineer cellular metabolism.
Ajikumar, Parayil Kumaran +6 more
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