Results 61 to 70 of about 6,856,593 (214)

Metabolomics and modelling approaches for systems metabolic engineering

, 2022
Metabolic engineering involves the manipulation of microbes to produce desirable compounds through genetic engineering or synthetic biology approaches.
Kulyk, Hanna, Yeo, Hock Chuan, Helmy, Mohamed, Khanijou, Jasmeet Kaur, Bellvert, Floriant, Chew, Wee, Bergès, Cécilia, Selvarajoo, Kumar, Khoo, Leng Wei, Ng, Pnelope   +9 more
core   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

A Novel 3D Model Co‐Culturing Breast Cancer Cells in Direct Contact with Patient‐Derived Mature Adipocytes Demonstrates Cell‐Type Specific Alterations in Phenotype and Chemosensitivity

Advanced Healthcare Materials, EarlyView.
A novel 3D GelMA co‐culture model enabled sustained direct contact between patient‐derived mature adipocytes and breast cancer cells, revealing subtype‐specific interactions. MDA‐MB‐231 co‐culture caused adipocyte perilipin‐1 loss and reduced chemotherapy responsiveness, while MCF7 cells showed partial epithelial‐mesenchymal transition; both cell lines
Jessika A. Wise, Margaret J. Currie, Helen R. Morrin, Gretel S. Major, Tim B. F. Woodfield, Khoon S. Lim, Elisabeth Phillips   +6 more
wiley   +1 more source

Identification of flux control in metabolic networks using non-equilibrium thermodynamics

, 2010
A method is presented to identify flux controlling reactions in metabolic networks using experimentally determined flux distributions. The method is based on the application of Ziegler's principle for the maximization of entropy production.
Bordel, S., Nielsen, Jens B., Velasco, Sergio, Nielsen, Jens B, Velasco, Sergio,, Nielsen, Jens B,, Jens Nielsen, Sergio Bordel   +7 more
core   +2 more sources

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Replication Data for Statistical Analysis

, 2020
Included here is a dataset with gesture form coding from the study author (Kate Mesh). Statistical analysis of the dataset was performed using R version 3.6.1 (R Core Team, 2019), with the package, lmer (Bates, Maechler, Bolcher & Walker, 2015).
Mesh, Kate
core   +1 more source

Radiative Thermal Management for Extreme Environments: Mechanisms and Design Strategies

Advanced Materials, EarlyView.
In this review, we discuss the fundamental mechanisms of radiative cooling and solar heating, material and structural design strategies, hybrid approaches integrating additional heat transfer pathways, and durability‐oriented designs addressing environmental stresses.
Hyung Rae Kim, Haeseong Kim, Joo Hwan Ko, Gil Ju Lee, Dae‐Hyeong Kim, Young Min Song   +5 more
wiley   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Identification of the Design Principles of Signaling Pathways for Metabolic Engineering [PDF]

The mitogen-activated protein kinase (MAPK) cascades are ubiquitous in eukaryotic signal transduction, and these pathways are conserved in cells from yeast to mammals.
Chachuat, Benoit, Bonvin, Dominique, Hatzimanikatis, Vassily, Radivojevic, Andrijana   +3 more
core   +1 more source