Results 231 to 240 of about 1,277,970 (342)

From Metabolic Syndrome to Cardiovascular-Kidney-Metabolic Syndrome and Systemic Metabolic Disorder: A Call to Recognize the Progressive Multisystemic Dysfunction. [PDF]

Anatol J Cardiol
Özyüncü N, Erol Ç.
europepmc   +1 more source

Impact of Intended Isocaloric Early versus Late Time‐Restricted Eating on Plasma Lipidome in Women with Overweight or Obesity: Secondary Analysis of the ChronoFast Trial

Advanced Science, EarlyView.
Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely, Mathias J. Gerl, Beeke Peters, Julia Schwarz, Bettina Schuppelius, Markus Damm, Jorge R. Soliz‐Rueda, Ratika Sehgal, Michail Lazaratos, Christian Klose, Kai Simons, Andreas F. H. Pfeiffer, Annette Schürmann, Achim Kramer, Andreas Michalsen, Olga Pivovarova‐Ramich   +15 more
wiley   +1 more source

Role of Metabolic Syndrome Traits on Infectious Diseases: A Mendelian Randomization Study. [PDF]

Int J Public Health
Cao S, Zeng Y, Zhang X, Tang J, Huang J, Lin G.   +5 more
europepmc   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

Advanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang, Jian Qi, Jialiang Wang, Zhipeng Wang, Yongguang Wang, Zongtao Hu, Ao Xu, Bo Hong, Hongzhi Wang   +8 more
wiley   +1 more source

Adiposity, the Metabolic Syndrome, and Breast Cancer in African-American and White American Women [PDF]

, 2007
David P. Rose, Steven M. Haffner, Jacques Baillargeon   +2 more
openalex   +1 more source

Pathophysiology and emerging biomarkers of cardiovascular-renal-hepato-metabolic syndrome. [PDF]

Front Cardiovasc Med
Nzobokela J, Muchaili L, Mwambungu A, Masenga SK, Kirabo A.   +4 more
europepmc   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

Internalized weight stigma, metabolic syndrome, and inflammation in postmenopausal women with obesity. [PDF]

Brain Behav Immun Health
Pearl RL, Anton SD, Saunders D, Hernandez M, Groshon LC, Sheynblyum M, Leget DL, McLaren C, Vial S, Gonzalez L, Wu K, Barsamyan G, Wadden TA.   +12 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

04.02 THE METABOLIC SYNDROME IS ASSOCIATED WITH CENTRAL AND PERIPHERAL ARTERIAL STIFFNESS IN YOUNG WOMEN BUT NOT IN MEN: THE MEDIATING ROLE OF INSULIN RESISTANCE AND LOW-GRADE INFLAMMATION. THE NORTHERN IRELAND YOUNG HEARTS PROJECT (NIYHP)

, 2007
Isabel Ferreira, Colin Boreham, J.W.R. Twisk, Alison Gallagher, Ian Young, Liam Murray, Coen D.A. Stehouwer   +6 more
openalex   +1 more source