Results 291 to 300 of about 4,435,982 (345)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Unveiling the significance of Netrin-1 and Netrin-4 in metabolic syndrome. [PDF]

Sci Rep
Kıran TR, Ayyıldız G, Keskin L, Erdem M.   +3 more
europepmc   +1 more source

Assesment of metaloproteinases and pro-inflammatory markers in patients with metabolic syndrome

, 2009
Flavia M. Gonçalves
openalex   +1 more source

Neighborhood Indices, Income, and Cardiovascular-Kidney-Metabolic Syndrome at the Census Tract Level.

JAMA Netw Open
Krishnan V, Huang X, McGowan C, Shah NS, Qureshi F, Minkovitz CS, Kershaw KN, Freedman AA, Miller GE, Lloyd-Jones DM, Khan SS.   +10 more
europepmc   +1 more source

Evaluation of nutritional interventions and their impact on metabolic syndrome risk markers in older adults. [PDF]

Front Nutr
Zhou L, Liu H, Ma Y.
europepmc   +1 more source

Factors Associated With Metabolic Syndrome in Korean Older Adults: A Cross-Sectional Analysis of KNHANES VIII (2019-2021). [PDF]

Health Sci Rep
Jang K, Seomun G.
europepmc   +1 more source

The Actinobacteria-to-Proteobacteria (A/P) Ratio: A Novel Oral Microbial Marker for Metabolic Syndrome. [PDF]

Int Dent J
Zhang J, Huang J, Li Y, Wu X, Guo F.
europepmc   +1 more source

GENDER DISPARITIES IN RISK OF METABOLIC SYNDROME AMONG OBESE YOUTH

Rashad Mahmood, Misbah Batool, Muhammad Shoaib, Najma Majeed, Ahmad Munir Qureshi, Tahira Nosheen   +5 more
openalex   +2 more sources

Metabolic syndrome duration and risk of frailty among midlife women: the Study of Women's Health Across the Nation. [PDF]

J Gerontol A Biol Sci Med Sci
Jackson EA, Karvonen-Gutierrez CA, Brooks MM, Strotmeyer E, Lange-Maia BS, Solomon DH, Hood MM, Derby CA.   +7 more
europepmc   +1 more source