Results 121 to 130 of about 42,467 (260)

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Fully Automated Plane Prescription in Cardiac MRI: A Prospective Cohort Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Accurate plane positioning is important for high‐quality cardiac MRI images but requires specialized training, limiting accessibility. Purpose To evaluate an automated plane positioning tool and compare it with manual planning. Study Type Prospective.
Benjamin Böttcher, Felix G. Meinel, Karolin K. Deyerberg, Lena‐Maria Watzke, Mathias Manzke, Margarita Gorodezky, Gaspar Delso, Antonia Dalmer, Anne Nerger, Marc‐André Weber, Ann‐Christin Klemenz   +10 more
wiley   +1 more source

Diagnostic contribution of metabolic workup for neonatal inherited metabolic disorders in the absence of expanded newborn screening

Scientific Reports, 2019
Inherited metabolic disorders (IMDs) in neonates are a diagnostic and therapeutic challenge for the neonatologist, with the priority being to rapidly flag the treatable diseases.
Alexandra Bower, Apolline Imbard, Jean-François Benoist, Samia Pichard, Odile Rigal, Olivier Baud, Manuel Schiff   +6 more
doaj   +1 more source

What is the impact of having a child dependent on home parenteral nutrition? A qualitative study in mothers and fathers

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Chronic intestinal failure (CIF) is a rare and complex disease, requiring home parenteral nutrition (HPN) to sustain growth and development. The impact on parents taking care for children with HPN remains underexplored. This qualitative study aimed to elucidate the experiences and challenges faced by parents in caring for HPN ...
Aysenur Demirok, Hedy A. van Oers, Marc A. Benninga, Lotte Haverman, Merit M. Tabbers   +4 more
wiley   +1 more source

Whole exome sequencing in energy deficiency inborn errors of metabolism: A systematic review

Molecular Genetics and Metabolism Reports
Broad biochemical complexity and frequent overlapping clinical symptoms of inborn errors of metabolism (IEM), especially in energy-deficient patients, make accurate diagnosis difficult.
Fatimah Diana Amin Nordin, Affandi Omar, Balqis Kamarudin, Timothy Simpson, Julaina Abdul Jalil, Yuh Fen Pung   +5 more
doaj   +1 more source

The landscape of CRISPR/Cas9 for inborn errors of metabolism.

Molecular Genetics and Metabolism, 2022
A. Leal, Nidhi Fnu, Eliana Benincore-Flórez, Angélica María Herreno-Pachón, O. Y. Echeverri-Peña, C. Alméciga-Díaz, S. Tomatsu   +6 more
semanticscholar   +1 more source

Hepatopulmonary syndrome in children and adolescents with portal hypertension in Brazil: A multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To describe the clinical and laboratory characteristics and outcomes of pediatric hepatopulmonary syndrome (HPS) secondary to portal hypertension (PH) in Brazil. Methods Fifty‐four pediatric patients diagnosed with PH and HPS according to the European Respiratory Society criteria were included in this multicenter retrospective study.
Leticia Drumond Alberto, Eleonora Druve Tavares Fagundes, Adriana Teixeira Rodrigues, Thaís Costa Nascentes Queiroz, Gustavo Valverde de Castro, Carlos Oscar Kieling, Sandra Maria Gonçalves Vieira, Natália Lamounier dos Martires Guerra, Natascha Silva Sandy, Gilda Porta, Irene Kazue Miura, Maria Ângela Bellomo Brandão, Gabriel Hessel, Adriana Maria Alves de Tommaso, Alexandre Rodrigues Ferreira   +14 more
wiley   +1 more source

Vitamin B12 deficiency in a pediatric patient with gastric obstruction and jejunal feeding dependence: A case report

JPGN Reports, EarlyView.
Abstract Pediatric B12 deficiency is most caused by insufficient dietary intake, malabsorption or autoimmune gastritis. We present a unique case of B12 deficiency in a pediatric patient with complex gastrointestinal anatomy and jejunal nutritional dependence nearly two decades after unsuccessful surgical intervention.
Angela H. Nguyen, Dorsey Bass, Rachel E. Herdes   +2 more
wiley   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source