Results 151 to 160 of about 2,125,068 (305)

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

British Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora, Maria Bove, Lisa Pia Agosti, Rossella Pia Palmieri, Mohsin Zafar, Paolo Tucci, Maria Grazia Morgese, Stefania Schiavone, Luigia Trabace   +8 more
wiley   +1 more source

Highly potent, brain‐penetrant EP2 receptor antagonists for the treatment of permanent focal cerebral ischaemia in male and female mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Cerebral ischaemia is a leading cause of death in older adults and imposes a substantial global economic burden. Recent studies indicate that inhibiting the Gαs‐coupled EP2 receptor reduces ischaemic brain injury by modulating neuroinflammation.
Zhen Jin, Chenyao Jiang, Eun Bee Cho, M. Dennis Leo, Jiukuan Hao, Jiawang Liu, Ying Yu, Jianxiong Jiang   +7 more
wiley   +1 more source

Advances in inborn errors of metabolism [PDF]

Journal of Human Genetics, 2019
Toshiyuki, Fukao, Kimitoshi, Nakamura
openaire   +2 more sources

Expanding the Biochemical Phenotype of ReNU Syndrome: A Case Report

Clinical Genetics, EarlyView.
This report detailed the clinical findings and the biochemical phenotype of a 3‐year‐old girl with ReNU syndrome. Circulating biomarkers and a muscle biopsy s uggested mild mitochondrial abnormalities. Severe plasmalogen deficiency was also observed, comparable to defects of peroxisomal plasmalogen biosynthesis.
Irene De Biase, McKall Johnson, Qinwen Mao, Vanina L. Taliercio, Stacey L. Cole   +4 more
wiley   +1 more source

Expanded newborn screening for inborn errors of metabolism in Isfahan Province: the first two-year report from Central Iran. [PDF]

Orphanet J Rare Dis
Mohajeri AM, Safaeian M, Shahpiri M, Dehkordi MA, Zeinalian M.   +4 more
europepmc   +1 more source

High Bleeding Rates After Tonsil Surgery in Denmark and Opportunities for Quality Improvement

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives To examine postoperative bleeding rates and associated patient and surgical factors after tonsil surgery in Denmark and identify targets for quality improvement. Design Multicentre cohort study using prospectively collected registry data.
Martin Mølhave, Nina M. Lyhne, Susanne H. Nielsen, Pernille Hahn, Jesper K. Holm, Therese Ovesen   +5 more
wiley   +1 more source

Case Report: When cardiomyopathy is the clue: late-presenting propionic acidemia manifesting as acute heart failure. [PDF]

Front Pediatr
Nti BK, Trapp N, Ali A, Lanpher B, Weatherhead J.   +4 more
europepmc   +1 more source

Stratum Corneum Biomarkers for Differentiating Irritant and Allergic Contact Dermatitis

Contact Dermatitis, EarlyView.
From 126 patients with irritant or allergic contact dermatitis of the hands, stratum corneum tape strips from patch test sites and lesional hand skin were collected and analysed for barrier and immune biomarkers, and machine learning models were trained to separate ICD from ACD.
F. L. de Boer, S. Kezic, Ivone Jakasa, Nique M. Grob, Nariman K. A. Metwally, Jϋrgen Claesen, Karen Ghauharali‐van der Vlugt, Femke S. Beers‐Stet, Wouter Ouwerkerk, Thomas Rustemeyer, Henk F. van der Molen   +10 more
wiley   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Vaccination of children with inborn errors of metabolism: safety, immunogenicity, and practical implications. [PDF]

Eur J Pediatr
Lipiński P, Jaczewska M, Jackowska T.
europepmc   +1 more source