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Metabolic Fluxes and Metabolic Engineering
Metabolic Engineering, 1999Metabolic engineering is the directed improvement of cellular properties through the modification of specific biochemical reactions or the introduction of new ones, with the use of recombinant DNA technology. As such, metabolic engineering emphasizes metabolic pathway integration and relies on metabolic fluxes as determinants of cell physiology and ...
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Metabolism and metabolic effects of ketoacids
The American Journal of Clinical Nutrition, 1980Administration of any of the three branched-chain amino or ketoacids necessarily yields the respective aminated or deaminated compound because the ubiquitous enzyme, branched-chain amino acid transaminase, catalyzes the reversible transfer of amino groups between the three amino acids and their ketoacids. Branched-chain amino acid transaminase activity
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Current Rheumatology Reports, 2010
We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
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We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
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Trends in Biotechnology, 2010
Metabolic networks have been studied for several decades, and sophisticated computational frameworks are needed to augment experimental approaches to harness these complex networks. BNICE (Biochemical Network Integrated Computational Explorer), a computational approach for the discovery of novel biochemical pathways that is based on biochemical ...
Soh, Keng Cher, Hatzimanikatis, Vassily
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Metabolic networks have been studied for several decades, and sophisticated computational frameworks are needed to augment experimental approaches to harness these complex networks. BNICE (Biochemical Network Integrated Computational Explorer), a computational approach for the discovery of novel biochemical pathways that is based on biochemical ...
Soh, Keng Cher, Hatzimanikatis, Vassily
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CONTINUUM: Lifelong Learning in Neurology, 2008
ABSTRACT Purpose of Review: Metabolic myopathies are genetic disorders that impair intermediary metabolism in skeletal muscle. Impairments in glycolysis/glycogenolysis (glycogen-storage disease), fatty acid transport and oxidation (fatty acid oxidation defects), and the mitochondrial respiratory chain ...
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ABSTRACT Purpose of Review: Metabolic myopathies are genetic disorders that impair intermediary metabolism in skeletal muscle. Impairments in glycolysis/glycogenolysis (glycogen-storage disease), fatty acid transport and oxidation (fatty acid oxidation defects), and the mitochondrial respiratory chain ...
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Metabolomics in cancer research and emerging applications in clinical oncology
Ca-A Cancer Journal for Clinicians, 2021Daniel R Schmidt +2 more
exaly
Targeting cancer metabolism in the era of precision oncology
Nature Reviews Drug Discovery, 2022Arantxa Gorostiaga +2 more
exaly
Metabolism and metabolic effects of hypoglycin
Biochimica et Biophysica Acta (BBA) - General Subjects, 1964J. Chang +3 more
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