Results 81 to 90 of about 321,422 (248)
ChemMedChem, Volume 21, Issue 1, January 2026.Green chemistry‐based late‐stage functionalization (LSF) of the anti‐proprotein convertase subtilisin/kexin type 9 (PCSK9) early lead compound 5c led to optimized analogs with improved metabolic stability/PCSK9 IC50 ratio. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key drug target for the treatment of different hypercholesterolemia ...
Lisa Giannessi +12 more
wiley +1 more source
Diabetology & Metabolic Syndrome, 2022 Background One hour plasma glucose concentration (1hPG) during an oral glucose tolerance test (OGTT) may be an alternative to 2-h plasma glucose concentration (2hPG) in the identification of individuals at increased risk of hyperglycaemia, although its ...
Vanessa Guerreiro +15 more
doaj +1 more source
Déficit Hídrico no Metabolismo da Soja em Semeaduras Antecipadas no Mato Grosso
, 2015 The soybean crop is subject to climatic adversities during their cycle, this being variable according to its sowing date. In the Mato Grosso state early soybean planting is already held by some producers, they opt for this, aiming mainly to escape the ...
E. Ferrari, A. Paz, A. D. Silva
semanticscholar +1 more source
CDG due to Defective Membrane Transporters: Update
Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley +1 more source
Egyptian Journal of Medical Human Genetics, 2023 Background The SHANK gene, located on chromosome 11q13.3-q13.4, encodes the SHANK2 protein with a function in neuronal synapses. An error in coding can alter the development of typical cognitive, linguistic and social skills.
David Molina Herranz +5 more
doaj +1 more source
Autoevaluación: Fisiopatología del metabolismo [PDF]
, 2013 La respiración, la circulación sanguínea, la contracción de un músculo o el mero pensamiento son fenómenos que obligan a que nuestro organismo esté en constante cambio, produciendo y consumiendo energía.
Andreu Periz, Lola +1 more
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Efecto del tratamiento dietoterápico de la obesidad sobre el metabolismo óseo
, 2016 La obesidad interfiere con el metabolismo oseo a traves de factores mecanicos, hormonales e inflamatorios. El principal tratamiento de dicha enfermedad es la dieta, modificacion de la cantidad y tipo de alimento.
J. Gómez +3 more
semanticscholar +1 more source
DÉFICIT HÍDRICO E ALTAS TEMPERATURAS NO METABOLISMO DA SOJA EM SEMEADURAS ANTECIPADAS
Nativa, 2015 A cultura da soja está sujeita a adversidades climáticas durante seu ciclo, sendo isto variável de acordo com a data de semeadura da mesma. No estado de Mato Grosso a semeadura antecipada da soja já é realizada por produtores rurais, estes optam por isso,
E. Ferrari, A. Paz, A. D. Silva
semanticscholar +1 more source
Obesity as a Risk Factor for Autoimmune Diseases: A Systematic Review and Meta‐Analysis
Obesity, Volume 34, Issue 1, Page 36-50, January 2026.Summary of the meta‐analysis including 26 studies (8 cross‐sectional, 18 longitudinal) investigating the association between obesity and autoimmune diseases. Findings show increased prevalence and incidence of rheumatoid arthritis, psoriasis, multiple sclerosis, and inflammatory bowel diseases in people with obesity, suggesting that obesity may ...
Ilaria Spatocco +12 more
wiley +1 more source
Bioscience Journal, 2009 A composição nutricional encontrada no laboratório e informações nutricionais presentes nos rótulos de alimentos industrializados podem divergir significativamente.
Daphne Santoro Leonardi +3 more
doaj