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Metabolomics for Investigating Physiological and Pathophysiological Processes
Physiological Reviews, 2019 Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput characterization of metabolites from cells, organs, tissues, or biofluids.
David Scott Wishart
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Using MetaboAnalyst 4.0 for Comprehensive and Integrative Metabolomics Data Analysis
Current Protocols in Bioinformatics, 2019MetaboAnalyst (https://www.metaboanalyst.ca) is an easy‐to‐use web‐based tool suite for comprehensive metabolomic data analysis, interpretation, and integration with other omics data.
Jasmine Chong, D. Wishart, J. Xia
semanticscholar +1 more source
Current Protocols in Molecular Biology, 2010
AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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Emerging applications of metabolomics in drug discovery and precision medicine
Nature Reviews Drug Discovery, 2016David Scott Wishart
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Clinica Chimica Acta, 2012
Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization.
Aihua, Zhang +3 more
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Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization.
Aihua, Zhang +3 more
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2019
The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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Artificial Intelligence in Metabolomics: A Current Review.
Trends in analytical chemistry : TRACMetabolomics and artificial intelligence (AI) form a synergistic partnership. Metabolomics generates large datasets comprising hundreds to thousands of metabolites with complex relationships.
Jinhua Chi +9 more
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Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
Medicinal research reviews (Print), 2022Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes mellitus and the leading cause of the end‐stage renal disease (ESRD).
Pedro R Pereira +5 more
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Recent advances in LC-MS-based metabolomics for clinical biomarker discovery.
Mass spectrometry reviews (Print), 2022The employment of liquid chromatography-mass spectrometry (LC-MS) untargeted and targeted metabolomics has led to the discovery of novel biomarkers and improved the understanding of various disease mechanisms.
Chao-Jung Chen +4 more
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