Results 1 to 10 of about 1,029 (201)
Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus [PDF]
Molecular Pharmacology, 2016 The delta family of ionotropic glutamate receptors consists of glutamate delta-1 (GluD1) and glutamate delta-2 receptors. We have previously shown that GluD1 knockout mice exhibit features of developmental delay, including impaired spine pruning and switch in the N-methyl-D-aspartate receptor subunit, which are relevant to autism and other ...
Pratyush S, Suryavanshi +5 more
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Brain Research BulletinMetabotropic glutamate receptors (mGluRs) are G-protein coupled receptors (GPCRs) that mediate slow glutamatergic signal transduction and regulate cell excitability in the central nervous system.
Megumi Taketo
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Metabotropic Glutamate Receptor 1 and Glutamate Signaling in Human Melanoma [PDF]
Cancer Research, 2007 Abstract Recently, several laboratories have started to investigate the involvement of glutamate signaling in cancer. In previous studies, we reported on a transgenic mouse model that develops melanoma spontaneously. Subsequent studies in these mice identified that the aberrant expression of metabotropic glutamate receptor 1 (GRM1) in ...
Jin, Namkoong +6 more
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Anti-mGluR1 encephalitis: Case illustration and systematic review
Frontiers in Neurology, 2023 BackgroundThe literature for immune-mediated neurological disorders is evolving like no other field of neurological illnesses. Many new antibodies or disorders have been described in the last decade.
Osama Khojah +6 more
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GRM1 (glutamate receptor, metabotropic 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2014 Review on GRM1, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Sierra, J, Chen, S
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L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets. [PDF]
PLoS ONE, 2014 L-Glutamate is a major oxidative fuel for the small intestine. However, few studies have demonstrated the effect of L-glutamate on the intestinal architecture and signaling of amino acids in the small intestine.
Meng Lin +7 more
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Metabotropic glutamate receptor type 1 in taste tissue [PDF]
The American Journal of Clinical Nutrition, 2009 l-Glutamate confers cognitive discrimination for umami taste (delicious or savory) and dietary information to the brain through the activation of G protein-coupled receptors in specialized taste receptor cells of the tongue. The taste heterologous receptor T1R1 plus T1R3 is not sufficient to detect umami taste in mice.
Ana, San Gabriel +3 more
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FMRP mediates mGluR5-dependent translation of amyloid precursor protein. [PDF]
PLoS Biology, 2007 Amyloid precursor protein (APP) facilitates synapse formation in the developing brain, while beta-amyloid (Abeta) accumulation, which is associated with Alzheimer disease, results in synaptic loss and impaired neurotransmission.
Cara J Westmark, James S Malter
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Group 1 metabotropic glutamate receptors and schizophrenia [PDF]
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2011 AbstractSchizophrenia is a prevalent neuropsychiatric disorder associated with perturbations in medial prefrontal cortex (PFC) excitability and connectivity. As such, research into the neurobiology of schizophrenia and related psychotic disorders has focused on understanding the possible role played by the major excitatory neurotransmitter glutamate in
DE BARTOLOMEIS, ANDREA, Szumlinski K. K.
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Neural Regeneration Research, 2021 Our previous studies have shown that glutamate and hippocampal neuron apoptosis are key signals and direct factors associated with diabetes-related depression, and structural and functional damage to the hippocampal neurovascular unit has been associated
Jian Liu +7 more
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