Results 111 to 120 of about 51,880 (241)
Role and Mechanism of Microglia in White Matter Injury Recovery in Ischemic Stroke
Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.Many studies have shown that stroke can cause microglia activation, and activated microglia differentiate into different types according to different time and region, and different types of microglia play an important role in the process of white matter recovery.
Yi‐Sha Guo +3 more
wiley +1 more source
Brain Research Bulletin, 2010 Excessive glutamatergic neurotransmission is considered an underlying factor of epilepsy. The modulation of the synaptic activity occurs both by the removal of glutamate from the synaptic cleft and by excitatory amino acid transporters (EAATs) and by modulation of glutamate receptors. The spontaneously epileptic rat (SER), a double mutant (zi/zi, tm/tm)
Jun-Ling Yu +10 more
openaire +3 more sources
Knockdown of spinal metabotropic glutamate receptor 1 (mGluR1) alleviates pain and restores opioid efficacy after nerve injury in rats [PDF]
, 2001 Marian E. Fundytus +7 more
openalex +1 more source
Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) is a human double‐stranded DNA virus that is responsible for the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), multicentric Castleman's disease (MCD), and KSHV inflammatory cytokine syndrome (KICS).
Quanyuan Wan, Andrew J. Tucker, Jun Zhao
wiley +1 more source
Effect of Aging on Gene Expression of Metabotropic Glutamate Receptor 5 and Glutamate Transporter‐1 in the Prefrontal Cortex of Schizophrenics [PDF]
, 2001 Hideho Shimada +3 more
openalex +1 more source
Astrocyte in Neurological Disease: Pathogenesis and Therapy
MedComm, Volume 6, Issue 8, August 2025.This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang +4 more
wiley +1 more source
Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
MedComm, Volume 6, Issue 8, August 2025.We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li +8 more
wiley +1 more source
Movement Disorders, Volume 40, Issue 8, Page 1561-1571, August 2025.Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico +14 more
wiley +1 more source
Metabotropic glutamate receptor 1 is associated with unfavorable prognosis in ER-negative and triple-negative breast cancer. [PDF]
Sci Rep, 2020 Bastiaansen AEM +11 more
europepmc +1 more source
British Journal of Pharmacology, Volume 182, Issue 15, Page 3612-3627, August 2025.Abstract Background and Purpose Several G protein‐coupled receptors (GPCRs) are known to homodimerise. Dimeric GPCRs may have different properties from their monomers, but the molecular basis and functional significance of GPCR dimerisation remain largely unknown.
Satoshi Asano +6 more
wiley +1 more source