Results 121 to 130 of about 51,880 (241)

Distinct Functional Roles of the Metabotropic Glutamate Receptors 1 and 5 in the Rat Globus Pallidus [PDF]

, 2003
Olga V. Poisik, Guido Mannaioni, Stephen F. Traynelis, Yoland Smith, P. Jeffrey Conn   +4 more
openalex   +1 more source

Functional Disconnections of the Pre‐Supplementary Motor Area in Patients With Post‐Stroke Aphasia and Their Associations With Neurotransmitters

CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.
Our findings suggest that functional connections of the preSMA are disrupted in PSA patients, which may be associated with neurotransmitter activity, possibly serving as the predictive markers for recovery of PSA. ABSTRACT Background The pre‐supplementary motor area (preSMA) is a critical region within domain‐general networks involved in speech ...
Daoran Wang, Xin Wang, Xinlei Xu, Kai Zheng, Dongdong Jiang, Guilan Huang, Lu Sun, Haobo Leng, Zimeng Yang, Guofu Zhang, Zhiyong Zhao, Caili Ren   +11 more
wiley   +1 more source

Role of G Protein-coupled Receptor Kinase 4 and ॆ-Arrestin 1 in Agonist-stimulated Metabotropic Glutamate Receptor 1 Internalization and Activation of Mitogen-activated Protein Kinases [PDF]

, 2003
Luisa Iacovelli, Lorena Salvatore, Loredana Capobianco, Antonietta Picascia, Eliana Barletta, Marianna Storto, Stefania Mariggiò, Michele Sallese, Antonio Porcellini, Ferdinando Nicoletti, Antonio De Blasi   +10 more
openalex   +1 more source

Amyloid‐Beta Pathology Increases Synaptic Engulfment by Glia in Feline Cognitive Dysfunction Syndrome: A Naturally Occurring Model of Alzheimer's Disease

European Journal of Neuroscience, Volume 62, Issue 3, August 2025.
McGeachan et al. demonstrate microgliosis, astrogliosis and increased synaptic engulfment by microglia and astrocytes in regions with Aβ plaques in aged cat brains and cats with cognitive dysfunction syndrome (CDS). Microglia and astrocytes also show enhanced internalisation of amyloid‐beta‐containing synapses near plaques.
Robert I. McGeachan, Lucy Ewbank, Meg Watt, Lorena Sordo, Alexandra Malbon, Muhammad Khalid F. Salamat, Makis Tzioras, Joao Miguel De Frias, Jane Tulloch, Fiona Houston, Danièlle Gunn‐Moore, Tara L. Spires‐Jones   +11 more
wiley   +1 more source

Amino Acid Mutagenesis of the Ligand Binding Site and the Dimer Interface of the Metabotropic Glutamate Receptor 1 [PDF]

, 2003
Toshihiro Sato, Yoshimi Shimada, Naoko Nagasawa, Shigetada Nakanishi, Hisato Jingami   +4 more
openalex   +1 more source

Efgartigimod as a Fast‐Acting Add‐On Therapy in Antibody–Mediated Autoimmune Encephalitis

European Journal of Neurology, Volume 32, Issue 8, August 2025.
ABSTRACT Background Autoimmune encephalitis (AE) is a severe neurological disorder that requires effective and safe treatment options. This study aimed to compare the efficacy and safety of intravenous methylprednisolone (IVMP) plus efgartigimod (IPE) versus IVMP alone or IVMP plus immunoglobulin (IPI) as initial treatments for antibody‐mediated AE ...
Zhuajin Bi, Wenzhong Kang, Ruihan Liu, Yan Jiang, Min Chen   +4 more
wiley   +1 more source

¹³¹I-IITM and ²¹¹At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 1. [PDF]

J Nucl Med, 2020
Xie L, Hanyu M, Fujinaga M, Zhang Y, Hu K, Minegishi K, Jiang C, Kurosawa F, Morokoshi Y, Li HK, Hasegawa S, Nagatsu K, Zhang MR.   +12 more
europepmc   +1 more source

Priming of Excitatory Synapses by α₁Adrenoceptor-Mediated Inhibition of Group III Metabotropic Glutamate Receptors [PDF]

, 2003
Grant R. Gordon, Jaideep S. Bains
openalex   +1 more source

Unlocking Relief: Investigating the Impact of a Fixed Combination of Acetyl‐L‐Carnitine and Palmitoylethanolamide on Traumatic Acute Low Back Pain

European Journal of Neurology, Volume 32, Issue 8, August 2025.
This monocentric observational study investigates a fixed combination of acetyl‐L‐carnitine, palmitoylethanolamide, and alpha‐lipoic acid in 48 patients with acute low back pain. Over 8 weeks, treatment led to significant reductions in neuropathic pain scores, decreased NSAID consumption, and improvements in quality of life, supporting its potential ...
Mattia Cominacini, Maria Teresa Valenti, Michele Braggio, Alberto Caramori, Ermes Vedovi, Luca Dalle Carbonare   +5 more
wiley   +1 more source

(2S,1’R, 2'R, 3'R)-2-(2,3-Dicarboxycyclopropyl)-glycine (DCG-IV): A type-specific agonist for metabotropic glutamate receptor negatively coupled with adenylate cyclase in rat hippocampus.

, 1994
Mutsumi Maruyama, Mariko Nakazawa
openalex   +1 more source