Results 151 to 160 of about 1,029 (201)

Synergism of virtual screening and medicinal chemistry: Identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1

, 2009
Tobias Noeske, Dina Trifanova, Valerjans Kauss, Steffen Renner, Chris G. Parsons, Gisbert Schneider, Tanja Weil   +6 more
openalex   +2 more sources

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors [PDF]

, 1998
Jian Cheng Tu, Bo Xiao, Joseph P. Yuan, Anthony A. Lanahan, Kathleen Leoffert, Min Li, David J. Linden, Paul F. Worley   +7 more
openalex   +1 more source

Protein networks associated with Group 1 metabotropic glutamate receptors

, 2015
Group I metabotropic Glutamate (mGlu) receptors play a pivotal role in synaptic transmission and neuronal plasticity in different brain areas. In particular, the mGlu1 receptor is critically involved in Long-Term Depression (LTD) in the cerebellar cortex, whereas the mGlu5 receptor is involved in both Long-Term Potentiation and LTD in the hippocampus ...
openaire   +1 more source

Improved Visualization and Specific Binding for Metabotropic Glutamate Receptor Subtype 1 (mGluR1) Using [11C]ITMM with Ultra-High Specific Activity in Small-Animal PET

, 2015
Tomoteru Yamasaki, Masayuki Fujinaga, Joji Yui, Hidekatsu Wakizaka, Tomoyuki Ohya, Nobuki Nengaki, Masanao Ogawa, Yoko Ikoma, Akiko Hatori, Lin Xie, Kazunori Kawamura, Ming‐Rong Zhang   +11 more
openalex   +2 more sources

Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin‐like growth factor 1 receptor

, 2014
Jessica L.F. Teh, Raj Shah, Seung‐Shick Shin, Yu Wen, Janice M. Mehnert, James S. Goydos, Suzie Chen   +6 more
openalex   +1 more source

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

, 2014
Huixian Wu, Chong Wang, Karen J. Gregory, Gye Won Han, Hyekyung P. Cho, Yan Xia, Colleen M. Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov, P. Jeffrey Conn, Raymond C. Stevens   +11 more
openalex   +1 more source

Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome

, 2011
Alexia M. Thomas, Nghiem Bui, Deanna Graham, Jennifer R. Perkins, Lisa A. Yuva‐Paylor, Richard Paylor   +5 more
openalex   +2 more sources

PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate.

, 2014
Tomoteru Yamasaki, Jun Maeda, Masayuki Fujinaga, Yuji Nagai, Akiko Hatori, Joji Yui, Lin Xie, Nobuki Nengaki, Ming‐Rong Zhang   +8 more
openalex   +1 more source

Ligand-Induced Dimeric Rearrangement of the Metabotropic Glutamate Receptor 1

Seibutsu Butsuri, 2005
Michihiro TATEYAMA, Yoshihiro KUBO
openaire   +2 more sources

The non-competitive metabotropic glutamate receptor-1 antagonist CPCCOEt inhibits the in vitro growth of human melanoma

, 2007
Helga Susanne Haas, Roswitha Pfragner, Veronika Siegl, Elisabeth Ingolić, Elfgard Heintz, Elisabeth Schraml, Konrad Schauenstein   +6 more
openalex   +2 more sources