Results 131 to 140 of about 44,093 (262)

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation

, 2017
Andrew S. Felts, Alice L. Rodriguez, Anna L. Blobaum, Ryan D. Morrison, Brittney S. Bates, Analisa Thompson Gray, Jerri M. Rook, Mohammed Noor Tantawy, Frank W. Byers, Sichen Chang, Daryl F. Venable, Vincent B. Luscombe, Gilles Tamagnan, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte   +18 more
openalex   +1 more source

Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats [PDF]

, 2009
Norio Yamamoto, Jean‐Jacques Soghomonian   +1 more
openalex   +1 more source

Vesicular Neurotransmitter Transporter Expression in Developing Postnatal Rodent Retina: GABA and Glycine Precede Glutamate

Journal of Neuroscience, 2003
Juliette Johnson, N. Tian, Matthew S. Caywood, R. Reimer, R. Edwards, D. Copenhagen   +5 more
semanticscholar   +1 more source

TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

Proceedings of the National Academy of Sciences of the United States of America, 2009
Chieko Koike, T. Obara, Y. Uriu, T. Numata, Rikako Sanuki, Kentaro Miyata, Toshiyuki Koyasu, S. Ueno, K. Funabiki, A. Tani, H. Ueda, M. Kondo, Y. Mori, M. Tachibana, T. Furukawa   +14 more
semanticscholar   +1 more source

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer.

Journal of Clinical Investigation, 2015
J. Ou, C. Vijayasarathy, L. Ziccardi, Shansup Chen, Yong Zeng, D. Marangoni, Jodie G. Pope, R. Bush, Zhijian Wu, Wei Li, P. Sieving   +10 more
semanticscholar   +1 more source

Synthesis and Evaluation in Monkey of [¹⁸F]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([¹⁸F]FIMX): A Promising Radioligand for PET Imaging of Brain Metabotropic Glutamate Receptor 1 (mGluR1) [PDF]

, 2013
Rong Xu, Paolo Zanotti‐Fregonara, Sami S. Zoghbi, Robert L. Gladding, Alicia E. Woock, Robert B. Innis, Victor W. Pike   +6 more
openalex   +1 more source

S2d1-6 Comparative analysis of the movement of the cytoplasmic domains between rhodopsin and metabotropic glutamate receptor(S2-d1: "Protein-Protein Interaction in the Signal Transduction of Rhodopsin",Symposia,Abstract,Meeting Program of EABS & BSJ 2006)

, 2006
Takahiro Yamashita, Akihisa Terakita, Yoshinori Shichida   +2 more
openalex   +2 more sources

Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2

Molecular Imaging and Biology, 2021
Gengyang Yuan, N. Guehl, Baohui Zheng, Xiying Qu, Sung-Hyun Moon, M. Dhaynaut, T. Shoup, S. Afshar, H. Kang, Zhaoda Zhang, G. El Fakhri, M. Normandin, A. Brownell   +12 more
semanticscholar   +1 more source

A Role for Nyctalopin, a Small Leucine-Rich Repeat Protein, in Localizing the TRP Melastatin 1 Channel to Retinal Depolarizing Bipolar Cell Dendrites

Journal of Neuroscience, 2011
J. Pearring, Pasano Bojang, Yin Shen, Chieko Koike, T. Furukawa, S. Nawy, R. Gregg   +6 more
semanticscholar   +1 more source

Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats [PDF]

, 2011
Manoranjan S. D’Souza, Athina Markou
openalex   +1 more source