Results 141 to 150 of about 51,960 (263)

Endocannabinoid signaling modulates neurons of the pedunculopontine nucleus (PPN) via astrocytes. [PDF]

, 2014
The pedunculopontine nucleus (PPN) is known as the cholinergic part of the reticular activating system (RAS) and it plays an important role in transitions of slow-wave sleep to REM sleep and wakefulness.
Antal, Miklós, Bíró, Tamás, Hegyi, Zoltán, Kovács, Adrienn, Kőszeghy, Áron, Pál, Balázs Zoltán, Szücs, Péter, Vincze, János   +7 more
core  

Synthesis and Evaluation in Monkey of [¹⁸F]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([¹⁸F]FIMX): A Promising Radioligand for PET Imaging of Brain Metabotropic Glutamate Receptor 1 (mGluR1)

, 2013
Rong Xu, Paolo Zanotti‐Fregonara, Sami S. Zoghbi, Robert L. Gladding, Alicia E. Woock, Robert B. Innis, Victor W. Pike   +6 more
openalex   +2 more sources

Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats

, 2009
Norio Yamamoto, Jean‐Jacques Soghomonian   +1 more
openalex   +1 more source

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation

, 2017
Andrew S. Felts, Alice L. Rodriguez, Anna L. Blobaum, Ryan D. Morrison, Brittney S. Bates, Analisa Thompson Gray, Jerri M. Rook, Mohammed Noor Tantawy, Frank W. Byers, Sichen Chang, Daryl F. Venable, Vincent B. Luscombe, Gilles Tamagnan, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte   +18 more
openalex   +1 more source

Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: A novel approach for controlling status epilepticus

, 2007
Feng Ru Tang, Peng Min Chen, Yong Tang, Mui Chiung Tsai, Wei Ling Lee   +4 more
openalex   +2 more sources

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist

, 2009
Atsushi Satoh, Yasushi Nagatomi, Yukari Hirata, Satoru Ito, Gentaroh Suzuki, Toshifumi Kimura, Shunsuke Maehara, Hirohiko Hikichi, Akio Satow, M. Hata, Hisashi Ohta, Hiroshi Kawamoto   +11 more
openalex   +1 more source

Endothelium glutamate receptors in brain pathology. [PDF]

Front Pharmacol
Pirozhkov SV, Vukolova MN, Bulgakova VV, Lutokhina YA, Bolevich SB, Sobolevsky AI, Yelshanskaya MV.   +6 more
europepmc   +1 more source

Radiosynthesis and preliminary evaluation of 4-[18F]fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as a new positron emission tomography ligand for metabotropic glutamate receptor subtype 1

, 2011
Tomoteru Yamasaki, Masayuki Fujinaga, Yuichiro Yoshida, Katsushi Kumata, Joji Yui, Kazunori Kawamura, Akiko Hatori, Toshimitsu Fukumura, Ming‐Rong Zhang   +8 more
openalex   +1 more source

Glycine Release Is Upregulated by Metabotropic Glutamate Receptor 1 in Mouse Hippocampus. [PDF]

Biomedicines
Raiteri L, Cerminara M, Puliti A, Pittaluga A.   +3 more
europepmc   +1 more source