Results 1 to 10 of about 22,867 (161)
Metabotropic Glutamate Receptor 7: A New Therapeutic Target in Neurodevelopmental Disorders [PDF]
Frontiers in Molecular Neuroscience, 2018 Neurodevelopmental disorders (NDDs) are characterized by a wide range of symptoms including delayed speech, intellectual disability, motor dysfunction, social deficits, breathing problems, structural abnormalities, and epilepsy.
Nicole M. Fisher +5 more
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Corrigendum: Metabotropic Glutamate Receptor 7: A New Therapeutic Target in Neurodevelopmental Disorders [PDF]
Frontiers in Molecular Neuroscience, 2018 Nicole M. Fisher +5 more
doaj +2 more sources
Constitutive activity of metabotropic glutamate receptor 7 [PDF]
, 2015 Paul J. Kammermeier
openalex +3 more sources
Can Metabotropic Glutamate Receptor 7 (mGluR 7) be a Novel Target for Analgesia? [PDF]
Journal of Clinical and Diagnostic Research, 2014 Introduction: The present study was carried out to study the role of metabotropic glutamate receptor 7 (mGluR7) using its agonist, N,N’-bis(diphenylmethyl)-1,-ethanediamine (AMN082) for nociceptive stimuli, in animal models.
Shivaprakash G +6 more
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European Psychiatry, 2023 Introduction Schizophrenia is a neuropsychiatric disorder characterised by positive, negative and cognitive behavioral symptoms. Despite years of research, the need for suitable therapy remains elusive.
R. O. Folarin, O. Owoeye, A. Malomo
doaj +1 more source
Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice [PDF]
PeerJ, 2015 Spinal astrocyte activation contributes to the pathogenesis of paclitaxel-induced neuropathic pain (PINP) in animal models. We examined glial fibrillary acidic protein (GFAP; an astrocyte marker) immunoreactivity and gene expression of GFAP, glutamate ...
Willias Masocha
doaj +2 more sources
Overexpression of mGluR7 in the Prefrontal Cortex Attenuates Autistic Behaviors in Mice
Frontiers in Cellular Neuroscience, 2021 Autism spectrum disorder (ASD) is associated with a range of abnormalities pertaining to socialization, communication, repetitive behaviors, and restricted interests. Owing to its complexity, the etiology of ASD remains incompletely understood.
Xiaona Wang +8 more
doaj +1 more source
Cells, 2022 Chronic psychosocial stress participates prominently in the etiology of various psychiatric conditions and comorbid somatic pathologies; however, suitable pharmacotherapy of these disorders is still of high medical need.
Karolyne A. R. Estrela +9 more
doaj +1 more source
Brazilian Journal of Otorhinolaryngology, 2019 Introduction: Sensorineural hearing loss is a common challenge all over the world, including a section of the young population. While there have been many published reports associating glutamate metabotropic receptor 7 with sensorineural hearing loss ...
Sanlin Xie +3 more
doaj +1 more source
Emotional Impairment and Persistent Upregulation of mGlu5 Receptor following Morphine Abstinence: Implications of an mGlu5-MOPr Interaction. [PDF]
, 2016 BACKGROUND: A difficult problem in treating opioid addicts is the maintenance of a drug-free state because of the negative emotional symptoms associated with withdrawal, which may trigger relapse.
Bailey, A +8 more
core +1 more source