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Modulation of Excitation by Metabotropic Glutamate Receptors
2007Metabotropic glutamate receptors, in contrast to ionotropic glutamate receptors, do not form ion channels but instead affect intracellular chemical messenger systems. They couple via GTP-binding proteins ("G-proteins") to a variety of effectors such as ion channels and thus give glutamate, the major excitatory transmitter in the CNS, the ability to ...
Marylka Uusisaari, Thomas Knöpfel
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Get receptive to metabotropic glutamate receptors
Current Opinion in Neurobiology, 1995Glutamate activates not only ionotropic glutamate receptors, but also G-protein-coupled receptors, called metabotropic glutamate receptors. Recent studies have revealed that these metabotropic receptors share distinctive structural properties and that they form a subgroup within the heptahelical receptor family.
Jean-Philippe Pin, Joël Bockaert
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Coordinate regulation of metabotropic glutamate receptors
Current Opinion in Neurobiology, 2001Recent studies aimed at identifying the mechanisms that regulate the signaling of metabotropic glutamate receptors (mGluRs) have revealed that both protein kinase and protein phosphatase activity are important in directly modulating mGluR function. The inter-relationship between phosphorylation and dephosphorylation of mGluRs seems to be an important ...
Scott D. Sorensen +2 more
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Sequence and expression of a metabotropic glutamate receptor
Nature, 1991The complementary DNA of a metabotropic glutamate receptor coupled to inositol phosphate/Ca2+ signal transduction has been cloned and characterized. This receptor shows no sequence similarity to conventional G protein-coupled receptors and has a unique structure with large hydrophilic sequences at both sides of seven putative membrane-spanning domains.
Yasuto Tanabe +4 more
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Metabotropic glutamate receptors
Pharmacology Biochemistry and Behavior, 2002openaire +3 more sources
Metabotropic glutamate receptors in the hypothalamus
Neuroscience Research Communications, 1997SORTINO M. A., CANONICO, Pier Luigi
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The metabotropic glutamate receptors
Trends in Pharmacological Sciences, 1995openaire +2 more sources
Molecular Recognition in Water Using Macrocyclic Synthetic Receptors
Chemical Reviews, 2021Luis Escobar, Pablo Ballester
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Barata, Brian I Rini
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