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The Involvement of the Endocannabinoid, Glutamatergic, and GABAergic Systems in PTSD. [PDF]
Grzesińska AD.
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Efficacy of early rituximab treatment in anti-mGluR1 encephalitis: a case report. [PDF]
Yamada K+11 more
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A metabotropic receptor for glycine
Nature Reviews Neuroscience, 2023Darran M. Yates
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Metabotropic glutamate receptors
Cell and Tissue Research, 2006Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
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Metabotropic glutamate receptors
Amino Acids, 2007l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
Andrzej Pilc, Krystyna Ossowska
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Metabotropic Glutamate Receptors and Neurodegeneration
2004Metabotropic glutamate (mGlu) receptors, which exert a modulatory effect on excitatory synaptic transmission, are considered as potential targets for neuroprotective drugs and the advent of potent and centrally available subtype-selective ligands has lead to an extensive investigation of the role of individual mGlu receptor subtypes in ...
BRUNO, Valeria Maria Gloria+7 more
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Structure of the metabotropic glutamate receptor
Current Opinion in Neurobiology, 2003In the twelve years since the molecular elucidation of the metabotropic glutamate receptor subtype 1, a class III family of G-protein-coupled receptors has emerged; members of this family include the calcium-sensing receptor, the GABA(B) receptor, some odorant receptors and some taste receptors.
Shigetada Nakanishi+2 more
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