, 2013 Legionella pneumophila is the causative agent of Legionnaires’ disease, severe pneumonia acquired from inhalation of contaminated water droplets. In the lung, L.
Harding, Clare R.
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ABSTRACT Legionella pneumophila is an opportunistic human pathogen that causes atypical pneumonia called Legionnaires’ Disease. To replicate within host cells, L. pneumophila injects up to 330 effector proteins into the host cytosol via a Dot/Icm type IV secretion ...
Dominik A. Machtens +7 more
openaire +1 more source
Phenotypic characterization of the membrane associated virulence factor Mip of Legionella pneumophila [PDF]
, 2016 Das Umweltbakterium Legionella pneumophila repliziert sich fakultativ intrazellulär in Protozoen, sowie in humanen alveolaren Makrophagen. Dies hat die Schädigung des Lungengewebes und zum Ausbruch einer Legionellose zur Folge.
Rasch, Janine
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Modulation of host polyubiquitination by the ankb f-box protein of Legionella pneumophila. [PDF]
, 2014 Legionella pneumophila is a facultative intracellular pathogen that infects a wide array of protozoan hosts and human alveolar macrophages. L. pneumophila is dependent on a functional Dot/Icm type IVB secretion system that translocates bacterial effector
Bruckert, William M.
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Biochemical and Structural Characterization of Divergent Members of the Protein Kinase Family [PDF]
The protein kinase family of enzymes catalyzes the transfer of the γ phosphate from an ATP molecule onto protein substrates. Using bioinformatic approaches, proteins with barely recognizable similarity to the known kinases can be found.
Osinski, Adam Krzysztof
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The manipulation of host transcription by the ANKH effector of legionella. [PDF]
, 2019 Legionella pneumophila is a Gram-negative facultative intracellular bacterium that can be found dispersed throughout freshwater environments, where it primarily parasitizes amoebae and other protozoan species.
Von Dwingelo, Juanita E.
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Structural Biology of Legionella pneumophila Effectors [PDF]
, 2019 Legionella pneumophila is a Gram-negative intracellular pathogen that causes Legionnaires’ disease and Pontiac fever in elderly or immunocompromised humans.
Voth, Kevin Andrew 1991-
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Legionella pneumophila-mediated host posttranslational modifications. [PDF]
J Mol Cell Biol, 2023 Yang Y +6 more
europepmc +1 more source
Complementary Immune Roles for Infected and Uninfected Cells During Legionella Pneumophila infection [PDF]
, 2015 The innate immune system responds to virulent pathogens, yet many pathogens manipulate host-signaling pathways, which should limit immune activation. The intracellular bacterium Legionella pneumophila is the cause of the severe pneumonia Legionnaire\u27s
Copenhaver, Alan M
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Anaplasma phagocytophilum remodels its host cell-derived vacuole into a protective niche by redecorating the vacuolar membrane with select Rab GTPases and bacterial proteins [PDF]
, 2011 Anaplasma phagocytophilum is an obligate intracellular bacterium that infects neutrophils to cause the emerging tick-transmitted disease, human granulocytic anaplasmosis (HGA).
Huang, Bernice
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