Results 291 to 300 of about 71,233 (313)
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Metagenomics

Letters in Applied Microbiology, 2008
The total number of prokaryotic cells on earth has been estimated to be approximately 4-6 x 10(30), with the majority of these being uncharacterized. This diversity represents a vast genetic bounty that may be exploited for the discovery of novel genes, entire metabolic pathways and potentially valuable end-products thereof.
R D, Sleator, C, Shortall, C, Hill
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Metagenomic Assembly: Reconstructing Genomes from Metagenomes

2021
Assembly of metagenomic sequence data into microbial genomes is of critical importance for disentangling community complexity and unraveling the functional capacity of microorganisms. The rapid development of sequencing technology and novel assembly algorithms have made it possible to reliably reconstruct hundreds to thousands of microbial genomes from
Wang Z.   +4 more
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Metagenomics

2011
Metagenomics has evolved over the last 3 decades from the analysis of single genes and their apparent diversity in an ecosystem to the provision of complex genetic information relating to whole ecosystems. Metagenomics is a vast subject area in terms of methodology, which encompasses a suite of molecular technologies employed to investigate genomic ...
Jack A, Gilbert   +5 more
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Metagenomic signatures of 86 microbial and viral metagenomes

Environmental Microbiology, 2009
SummaryPrevious studies have shown that dinucleotide abundances capture the majority of variation in genome signatures and are useful for quantifying lateral gene transfer and building molecular phylogenies. Metagenomes contain a mixture of individual genomes, and might be expected to lack compositional signatures.
Willner, Dana   +2 more
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PCR in Metagenomics

2017
Metagenomics approach involves direct genetic analysis of environmental samples, evading the tedious culturing process. Polymerase chain reaction is one invaluable tool used for such analyses. Here, we describe one protocol for metagenomic DNA isolation that gives inhibitor-free DNA suitable for PCR and other genetic manipulations.
Tina Kollannoor Johny, Sarita G. Bhat
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Viral metagenomics

Nature Reviews Microbiology, 2005
Viruses, most of which infect microorganisms, are the most abundant biological entities on the planet. Identifying and measuring the community dynamics of viruses in the environment is complicated because less than one percent of microbial hosts have been cultivated. Also, there is no single gene that is common to all viral genomes, so total uncultured
Robert A, Edwards, Forest, Rohwer
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Metagenomics and Metatranscriptomics

2022
International ...
Guyomar, Cervin, Lemaitre, Claire
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The metagenomics of soil

Nature Reviews Microbiology, 2005
Phylogenetic surveys of soil ecosystems have shown that the number of prokaryotic species found in a single sample exceeds that of known cultured prokaryotes. Soil metagenomics, which comprises isolation of soil DNA and the production and screening of clone libraries, can provide a cultivation-independent assessment of the largely untapped genetic ...
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