Results 141 to 150 of about 149,337 (415)
Recently, dysbiosis in the human gut microbiome and shifts in the relative abundances of several bacterial species have been recognized as important factors in colorectal cancer (CRC).
Ankit Gupta+12 more
doaj +3 more sources
Carbapenem-resistant Enterobacteriaceae (CRE) are an urgent public health concern. Rapid identification of the resistance genes, their mobilization capacity, and strains carrying them is essential to direct hospital resources to prevent spread and ...
Nicole D. Pecora+8 more
doaj +1 more source
MCUIUC -- A New Framework for Metagenomic Read Compression [PDF]
Metagenomics is an emerging field of molecular biology concerned with analyzing the genomes of environmental samples comprising many different diverse organisms. Given the nature of metagenomic data, one usually has to sequence the genomic material of all organisms in a batch, leading to a mix of reads coming from different DNA sequences.
arxiv
Dirichlet multinomial mixtures: generative models for microbial metagenomics [PDF]
We introduce Dirichlet multinomial mixtures (DMM) for the probabilistic modelling of microbial metagenomics data. This data can be represented as a frequency matrix giving the number of times each taxa is observed in each sample.
Harris, Keith+2 more
core +4 more sources
Metagenomics for neurological infections — expanding our imagination
Over the past two decades, the diagnosis rate for patients with encephalitis has remained poor despite advances in pathogen-specific testing such as PCR and antigen assays.
P. Ramachandran, M. Wilson
semanticscholar +1 more source
metaSPAdes: a new versatile de novo metagenomics assembler [PDF]
While metagenomics has emerged as a technology of choice for analyzing bacterial populations, assembly of metagenomic data remains difficult thus stifling biological discoveries. metaSPAdes is a new assembler that addresses the challenge of metagenome analysis and capitalizes on computational ideas that proved to be useful in assemblies of single cells
arxiv
Although using anammox communities for efficient wastewater treatment has attracted much attention, the pure anammox bacteria are difficult to obtain, and the potential roles of symbiotic bacteria in anammox performance are still elusive.
Yunpeng Zhao+7 more
semanticscholar +1 more source
AbstractCharacterisation of new viruses is often hindered by difficulties in amplifying them in cell culture, limited antigenic/serological cross‐reactivity or the lack of nucleic acid hybridisation to known viral sequences. Numerous molecular methods have been used to genetically characterise new viruses without prior in vitro replication or the use ...
openaire +2 more sources
A Bioinformatician's Guide to Metagenomics [PDF]
SUMMARYAs random shotgun metagenomic projects proliferate and become the dominant source of publicly available sequence data, procedures for the best practices in their execution and analysis become increasingly important. Based on our experience at the Joint Genome Institute, we describe the chain of decisions accompanying a metagenomic project from ...
Kunin, V.+4 more
openaire +4 more sources