Complementary Metagenomic Approaches Improve Reconstruction of Microbial Diversity in a Forest Soil. [PDF]
Soil ecosystems harbor diverse microorganisms and yet remain only partially characterized as neither single-cell sequencing nor whole-community sequencing offers a complete picture of these complex communities.
Alteio, LV +12 more
core +3 more sources
Salar de Atacama is located approximately 55 km south of San Pedro de Atacama in the Antofagasta region, Chile. The high UV irradiation and salt concentration and extreme drought make Salar de Atacama an ideal site to search for novel soil microorganisms
Ignacio Ramos-Tapia +5 more
doaj +1 more source
Diabetes mellitus and related complications are among the most important problems of the world-leading healthcare systems. Despite their priority, molecular and genetic aspects of diabetes pathogenesis are poorly understood; however, the involvement of ...
Yuliya Dvoretskaya +4 more
doaj +1 more source
Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]
This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
Ashby, Deborah +26 more
core +7 more sources
Background Cholera can result in the expulsion of important microbiota from the gut and result in death if left untreated. The disease transmits mainly via drinking water carrying Vibrio cholerae; and household contacts (HHC) of cholera patients are at ...
Shirajum Monira +18 more
doaj +1 more source
Characterisation of three novel α-L-arabinofuranosidases from a compost metagenome
Background The importance of the accessory enzymes such as α-L-arabinofuranosidases (AFases) in synergistic interactions within cellulolytic mixtures has introduced a paradigm shift in the search for hydrolytic enzymes.
Brent Fortune +5 more
doaj +1 more source
Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D. +4 more
core +1 more source
MEGAHIT: An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph [PDF]
MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252Gbps in 44.1 hours and 99.6 hours on a single computing node with and ...
Lam, Tak-Wah +4 more
core +2 more sources
From metagenomics to the metagenome: Conceptual change and the rhetoric of translational genomic research [PDF]
As the international genomic research community moves from the tool-making efforts of the Human Genome Project into biomedical applications of those tools, new metaphors are being suggested as useful to understanding how our genes work – and for ...
Huss, John Edward, Juengst, Eric Thomas
core +1 more source
A Vavilovian approach to discovering crop-associated microbes with potential to enhance plant immunity [PDF]
Through active associations with a diverse community of largely non-pathogenic microbes, a plant may be thought of as possessing an “extended genotype,” an interactive cross-organismal genome with potential, exploitable implications for plant immunity ...
Broders, Kirk +2 more
core +3 more sources

