Results 11 to 20 of about 117,934 (343)

Clinical metagenomics [PDF]

open access: yesNature Reviews Genetics, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
C. Chiu, Steve Miller
semanticscholar   +5 more sources

Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software [PDF]

open access: yesNature Methods, 2017
Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome data, but a lack of consensus about benchmarking complicates performance assessment.
A. Sczyrba   +66 more
semanticscholar   +11 more sources

Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics

open access: yesMicrobiome, 2019
Background Mosquitoes are the most important invertebrate viral vectors in humans and harbor a high diversity of understudied viruses, which has been shown in many mosquito virome studies in recent years.
Chenyan Shi   +7 more
doaj   +2 more sources

Metagenomics: An Effective Approach for Exploring Microbial Diversity and Functions

open access: yesFoods, 2023
Various fields have been identified in the “omics” era, such as genomics, proteomics, transcriptomics, metabolomics, phenomics, and metagenomics. Among these, metagenomics has enabled a significant increase in discoveries related to the microbial world ...
N. N. Nam   +3 more
semanticscholar   +1 more source

MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph [PDF]

open access: yesBioinform., 2014
MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252 Gbps in 44.1 and 99.6 h on a single computing node with and without a ...
Dinghua Li   +4 more
semanticscholar   +1 more source

Metagenomics and antibiotics [PDF]

open access: yesClinical Microbiology and Infection, 2012
Most of the bacterial species that form part of the biosphere have never been cultivated. In this situation, a comprehensive study of bacterial communities requires the utilization of non-culture-based methods, which have been named metagenomics.
María Blanca Sánchez   +3 more
openaire   +2 more sources

A Primer on Metagenomics [PDF]

open access: yesPLoS Computational Biology, 2010
Metagenomics is a discipline that enables the genomic study of uncultured microorganisms. Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of the microbial world.
Bourne, Philip E.   +3 more
openaire   +6 more sources

Metagenomics and probiotics [PDF]

open access: yesClinical Microbiology and Infection, 2012
The development of extensive sequencing methods has allowed metagenomic studies on the human gut microbiome to be carried out. This has tremendously increased our knowledge on gut microbiota composition and activity, allowing microbiota aberrations related to different diseases to be identified.
Gueimonde Fernández, Miguel   +1 more
openaire   +4 more sources

Metagenomic Thermometer

open access: yesDNA Research, 2022
AbstractVarious microorganisms exist in environments, and each of which has an optimal growth temperature (OGT). The relationship between genomic information and OGT of each species has long been studied, and one such study revealed that OGT of prokaryotes can be accurately predicted based on the fraction of seven amino acids (IVYWREL) among all ...
Masaomi Kurokawa   +6 more
openaire   +2 more sources

Advances in Metagenomics and Its Application in Environmental Microorganisms

open access: yesFrontiers in Microbiology, 2021
Metagenomics is a new approach to study microorganisms obtained from a specific environment by functional gene screening or sequencing analysis.
Lu Zhang   +12 more
semanticscholar   +1 more source

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