Results 231 to 240 of about 149,337 (415)

Preconception maternal gut dysbiosis affects enteric nervous system development and disease susceptibility in offspring via the GPR41–GDNF/RET/SOX10 signaling pathway

iMeta, EarlyView.
Preconception administration of antibiotics to female mice reduces the abundance of Limosilactobacillus reuteri in the maternal gut microbiota during pregnancy, subsequently affecting propionate levels. Decreased propionate levels downregulated the expression of Gdnf/Ret/Sox10 mediated by GPR41, leading to abnormal development of the enteric nervous ...
Cunzheng Zhang, Yuzhu Chen, Ruqiao Duan, Yiming Zhang, Haonan Zheng, Jindong Zhang, Tao Zhang, Jingxian Xu, Kailong Li, Fei Pei, Liping Duan   +10 more
wiley   +1 more source

METAGENE-1: Metagenomic Foundation Model for Pandemic Monitoring [PDF]

arXiv
We pretrain METAGENE-1, a 7-billion-parameter autoregressive transformer model, which we refer to as a metagenomic foundation model, on a novel corpus of diverse metagenomic DNA and RNA sequences comprising over 1.5 trillion base pairs. This dataset is sourced from a large collection of human wastewater samples, processed and sequenced using deep ...
arxiv  

Interplay of metagenomics and in vitro compartmentalization [PDF]

, 2008
Manuel Ferrer, Ana Beloqui, José María Vieites, Marı́a-Eugenia Guazzaroni, Ilana Berger Fridman, Amir Aharoni   +5 more
openalex   +1 more source

Gut microbiota in cancer: From molecular mechanisms to precision medicine applications

iMeta, EarlyView.
The gut microbiota–cancer interaction functions through multi‐level biological mechanisms, forming the basis for both diagnostic and therapeutic applications. Current technical and biological challenges drive the field toward precision medicine approaches, aiming to integrate multi‐dimensional data for optimized, personalized cancer treatments.
Weihua Xiao, Qiong Chen, Chunjiao Liu, Yueer Yu, Tianliang Liu, Yang Jin, Haifen Ma, Shifu Chen, Chao Jiang   +8 more
wiley   +1 more source

Adalimumab therapy is associated with increased faecal short chain fatty acids in hidradenitis suppurativa

Experimental Dermatology, Volume 31, Issue 12, Page 1872-1880, December 2022., 2022
Abstract Altered gut microbiota composition has been observed in individuals with hidradenitis suppurutiva (HS) and many other inflammatory diseases, including obesity, type 1 and type 2 diabetes. Here, we addressed whether adalimumab, a systemic anti‐inflammatory therapy, may impact the microbiota biochemical profile, particularly on beneficial ...
Artiene Tatian, Sara Bordbar, Samuel Der Sarkissian, Jane A. Woods, Geoffrey D. Cains, Chun Wie Chong, Eliana Mariño, John W. Frew   +7 more
wiley   +1 more source

Metagenomics: Access to Unculturable Microbes in the Environment

, 2006
Nobutada Kimura
openalex   +2 more sources

Gene prediction in metagenomic fragments: A large scale machine learning approach [PDF]

, 2008
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rolf Daniel, Burkhard Morgenstern, Peter Meinicke   +5 more
openalex   +1 more source

MDIPID: Microbiota‐drug interaction and disease phenotype interrelation database

iMeta, EarlyView.
The intricate bidirectional relationships among microbiota, microbial proteins, drugs, and diseases are essential for advancing precision medicine and minimizing adverse drug reactions. However, there are currently no data resources that comprehensively describe these valuable interactions.
Jiayi Yin, Hui Ma, Yuting Qi, Qingwei Zhao, Su Zeng, Fengcheng Li, Feng Zhu   +6 more
wiley   +1 more source

Spaceflight redefines ageing‐associated microbiota

iMeta, EarlyView.
Spaceflight reshapes microbiota and immune function, mitigating some ageing effects while accelerating immune aging, revealing crucial insights for astronaut health and longevity in space missions.
Yuan Sun, Sai Liu, Long Chen, Zheng Zhou, Mengyu Ma, Jinran Li, Yi Lu, Yiting Shi, Tingting Yao, Ruizhi Feng, Qiulun Lu, Fatimah Qassadi, Philip M. Williams, Tanya M. Monaghan, Guangji Wang, Zheying Zhu, Xinuo Li   +16 more
wiley   +1 more source

Microbiologically influenced corrosion in aluminium alloys and premier techniques for comprehensive identification and characterization across diverse metal types

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Microbiologically influenced corrosion (MIC) is acknowledged as a significant type of corrosion due to its extensive impact on metal/alloy surfaces. As MIC accounts for 20% of all corrosion instances, it is a critical factor causing service failure of engineering materials such as steel and aluminium alloy.
Brinda, M S Divyashree, Suma A Rao, Padmalatha Rao, Lavanya Mulky   +4 more
wiley   +1 more source