Results 51 to 60 of about 133,015 (283)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Investigation into the effects of varied pressure application techniques on microstructural evolution and thermal conductivity of SiCp/Al composites manufactured via stir casting

Journal of Materials Research and Technology
The elimination of defects is critical for enhancing microstructural uniformity and thermal conductivity of Al composites prepared by stir casting. External pressure enhances the densification of composites. Exploring its influence on microstructural and
Yuncong Shang, Wenda Zhang, Heqian Song, Lin He, Hongbin Liu, Zhiqiang Guo, Yuxin Li, Hong Xu   +7 more
doaj   +1 more source

Morphology investigation on direct current pulsed gas tungsten arc welded additive layer manufactured Ti6Al4V alloy [PDF]

, 2011
The effects of pulsed gas tungsten arc weldingparameters on the morphology of additive layer manufacturedTi6Al4V has been investigated in this study.
Rush, M. T., Wang, Fude, Williams, Stewart W.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Plastic deformation behavior and dynamic recrystallization of Inconel 625 superalloy fabricated by directed energy deposition

Materials & Design, 2020
In this study, the hot plastic deformation behavior and dynamic recrystallization (DRX) phenomenon of Inconel 625 superalloy prepared by directed energy deposition (DED) are investigated by carrying out hot compression tests.
Y.L. Hu, X. Lin, Y.L. Li, S.Y. Zhang, X.H. Gao, F.G. Liu, X. Li, W.D. Huang   +7 more
doaj   +1 more source

A novel methodology of design for Additive Manufacturing applied to Additive Laser Manufacturing process [PDF]

, 2014
International audienceNowadays, due to rapid prototyping processes improvements, a functional metal part can be built directly by Additive Manufacturing. It is now accepted that these new processes can increase productivity while enabling a mass and cost
Hascoët, Jean-Yves, Kerbrat, Olivier, Mognol, Pascal, Ponche, Rémi   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

High-throughput first-principles investigation on grain boundary segregation of alloying elements in ferritic steel

Journal of Materials Research and Technology, 2023
By employing high-throughput first-principles calculations, the segregation capacity of fifteen widely used metallic alloying elements (viz., Be, Mn, Co, Cr, Ni, Al, Mo, W, Mg, Ta, Nb, Sb, Sn, Zr, and Bi) at ∑3 grain boundary in low alloy ferritic steel,
Mengmeng Yang, Jiaying Zhou, Haijun Huang, Shuo Cao, Qing-Miao Hu, Wei Li, Qingjun Chen, Yanxin Qiao, Hao Wang   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Metal additive manufacturing in aerospace: A review

Materials & Design, 2021
Metal additive manufacturing involves manufacturing techniques that add material to produce metallic components, typically layer by layer. The substantial growth in this technology is partly driven by its opportunity for commercial and performance ...
Byron Blakey-Milner, Paul Gradl, Glen Snedden, Michael Brooks, Jean Pitot, Elena Lopez, Martin Leary, Filippo Berto, Anton du Plessis   +8 more
doaj   +1 more source