Results 31 to 40 of about 353,777 (261)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The charge transfer between metal and support is significant for catalysis, but little attention has been focused on charge transfer tuned by metal size.
Qiang-Qiang Yan +8 more
doaj +1 more source
Numerical simulation study on heat transfer enhancement of a heat exchanger wrapped with metal foam
Tube bank wrapped with metal foam is a new compact heat exchanger with high specific surface area. The thermo-hydraulic properties of metal foam is key parameters to determine the structure of the tube bank covered on metal foam. Previous studies focused
Kang Chen +3 more
doaj +1 more source
crash3: cosmological radiative transfer through metals [PDF]
Here we introduce CRASH3, the latest release of the 3D radiative transfer code CRASH. In its current implementation CRASH3 integrates into the reference algorithm the code Cloudy to evaluate the ionisation states of metals, self-consistently with the radiative transfer through H and He.
Graziani, L., Maselli, A., Ciardi, B.
openaire +5 more sources
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The procedure of determination of the temperature field of steel slug at heating in continuous furnace taking into account dependence of the temperature conductivity coefficient on temperature is stated.
V. I. Timoshposki +3 more
doaj
Improving microstructure and mechanical properties of WAAMed Al with UV introduced via a torch clamp
Ultrasonic assisting is considered to be a promising technology for industrial applications due to its ability to improve the quality of the WAAMed component.
Hao Jiao +3 more
doaj +1 more source

