Results 141 to 150 of about 21,893 (312)

Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM-1 [PDF]

open access: yes, 2014
In an effort to characterize the roles of each metal ion in metallo-β-lactamase NDM-1, heterodimetallic analogues (CoCo-, ZnCo-, and CoCd-) of the enzyme were generated and characterized. UV–vis, 1H NMR, EPR, and EXAFS spectroscopies were used to confirm
Alyssa Hetrick   +94 more
core   +3 more sources

Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2004
Background Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of arterial aneurysms through increased proteolysis of extracellular matrix proteins.
Duman Can   +5 more
doaj   +1 more source

Metalloprotein-inhibitor binding: human carbonic anhydrase II as a model for probing metal-ligand interactions in a metalloprotein active site.

open access: yesInorganic Chemistry, 2013
An ever-increasing number of metalloproteins are being discovered that play essential roles in physiological processes. Inhibitors of these proteins have significant potential for the treatment of human disease, but clinical success of these compounds ...
David P. Martin   +2 more
semanticscholar   +1 more source

Moisturizing Treatment Outcomes: A Comparative Study of Diabetic and Nondiabetic Skin, Associated With the Presence or Absence of Dermatoporosis

open access: yesDermatological Reviews, Volume 6, Issue 3, June 2025.
ABSTRACT Background Skin disorders are highly common in type 1 and 2 diabetes mellitus patients. This study assessed the effects of a moisturizing formulation on photoprotected (volar forearm) and photoexposed (dorsal hand) skin in diabetic and nondiabetic participants, with or without stage I dermatoporosis, comparing it to a reference product ...
Juliana Rodrigues Pinto   +2 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, Volume 5, Issue 3, June 2025.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

Effect of ELF e.m. fields on metalloprotein redox-active sites

open access: yes, 2007
The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals.
Badon, T.   +6 more
core  

Biochemical metal accumulation effects and metalloprotein metal detoxification in environmentally exposed tropical Perna perna mussels

open access: yesEcotoxicology and Environmental Safety, 2021
Marine bivalves have been widely applied as environmental contamination bioindicators, although studies concerning tropical species are less available compared to temperate climate species. Assessments regarding Perna perna mytilid mussels, in particular,
Rachel Ann Hauser-Davis   +11 more
doaj  

The in crystallo optical spectroscopy toolbox

open access: yesJournal of Applied Crystallography, Volume 58, Issue 3, Page 1068-1078, June 2025.
The rise of time‐resolved macromolecular crystallography has been accompanied by renewed interest in companion biophysical characterization methods applicable to molecules both in solution and in crystallo. Here, we present a workflow and a graphical interface for analysing spectroscopic data collected on macromolecular crystals.Over the past ten years,
Nicolas Caramello   +3 more
wiley   +1 more source

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