Results 1 to 10 of about 6,393 (222)

Stressless sampling to improve diagnostics of catecholamine excess: new assay to determine metanephrines in saliva [PDF]

Endocrine Connections
Determination of metanephrines in saliva has been reported as a pain- and hazard-free alternative to plasma-based tests with a potential to reduce false-positive results during diagnostic work-up for neuroendocrine tumours.
Per M Thorsby, Sandra R Dahl, Tone Smetop, Tone Hæg Lindholm, Svetlana N Zykova   +4 more
doaj   +2 more sources

Bilateral pheochromocytoma as a late presentation of neurofibromatosis type 1 [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Neurofibromatosis type 1 (NF1) is an autosomal dominant condition predisposing to tumors, including pheochromocytomas and paragangliomas. Reported penetrance is close to 100%, but clinical presentation is highly variable.
Helena Urbano Ferreira, Maria Luísa Sacramento, Juliana Gonçalves, Elisabete Rios, Joana Queirós, Sandra Belo   +5 more
doaj   +2 more sources

A potentially dangerous case of mistaken identity: giant asymptomatic composite phaeochromocytoma [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Small clinically silent phaeochromocytoma (PCC) can be identified in modern clinical practice as apparent adrenal incidentaloma or during screening of patients with familial tumour syndromes.
Annabelle G Hayes, Morton G Burt
doaj   +2 more sources

Urinary Free Metanephrines for Diagnosis of Pheochromocytoma and Paraganglioma [PDF]

Endocrinology and Metabolism, 2021
Background Pheochromocytoma and paraganglioma (PPGL) is diagnosed through biochemical confirmation of excessive catecholamines in urine and plasma. Recent technological developments have allowed us to measure urinary free metanephrines; however, the ...
Jiyeon Ahn, Ji Yun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Soo-Youn Lee, Jae Hyeon Kim   +6 more
doaj   +1 more source

Adrenal Ganglioneuroma: A Rare Incidentaloma [PDF]

National Journal of Laboratory Medicine, 2021
Adrenal ganglioneuroma is a very rare tumour of sympathetic nervous system that originate from neural crest sympathogonia which are completely undifferentiated cells of the sympathetic nervous system, constituting 20 to 30% of all Ganglioneuromas (GNs).
Rashmi Rani Bharti, Sanjay Kumar, Bipin Kumar   +2 more
doaj   +1 more source

An uncommon case of pheochromocytoma with positive biochemical workup and absence of tumor [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Pheochromocytomas are rare neuroendocrine tumors derived from adrenal chromaffin cells that result in hyperactivity of the sympathetic nervous system. We present the case of a patient with biochemical evidence of pheochromocytoma, but surgical pathology ...
Nicole Chan, Ronald P Kaufman, Nada Farhat, Grace Y Kim   +3 more
doaj   +2 more sources

Urine-normetanephrine, a predictor of mortality risk in patients with adrenal adenomas [PDF]

Scientific Reports
Urine-metanephrines are used in the screening for pheochromocytomas in patients with adrenal incidentalomas, but their potential as markers for mortality in patients with adrenal adenomas has not been studied. A retrospective cohort study was designed to
Albin Kjellbom, Magnus Löndahl, Malin Danielsson, Henrik Olsen, Ola Lindgren   +4 more
doaj   +2 more sources

Non-Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor. [PDF]

IJU Case Rep
ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally.
Wainstein M, Aslot V, Dennie F, Wainstein M, Chandrasekar T.   +4 more
europepmc   +2 more sources

Rare Association Between Neurofibromatosis Type 1 and Adrenocortical Carcinoma. [PDF]

Clin Case Rep
Axial slice CT abdomen pelvis with portal venous contrast, revealing a well circumscribed 22 × 20 × 22 mm left adrenocortical adenocarcinoma (ACC) in a patient with neurofibromatosis type 1 (NF1). ABSTRACT Although rare, adrenocortical carcinoma (ACC) should be considered in individuals with neurofibromatosis type 1 (NF1) presenting with adrenal ...
Pluim Z, Choi JDW, Kakala B, Wong J, Clifton-Bligh R, Sywak M, Howle J.   +6 more
europepmc   +2 more sources

Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension

Frontiers in Endocrinology, 2022
IntroductionNeuroblastoma (NB) is a pediatric cancer of the developing sympathetic nervous system. It produces and releases metanephrines, which are used as biomarkers for diagnosis in plasma and urine. However, plasma catecholamine concentrations remain
Annick Mühlethaler-Mottet, Silvia Uccella, Silvia Uccella, Deborah Marchiori, Stefano La Rosa, Stefano La Rosa, Jean Daraspe, Katia Balmas Bourloud, Maja Beck Popovic, Philippe J. Eugster, Eric Grouzmann, Karim Abid   +11 more
doaj   +1 more source