Results 11 to 20 of about 88,646 (328)

Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond.

Gastroenterology, 2021
The mucosa of the body of the stomach (i.e., the gastric corpus) employs two overlapping, depth-dependent mechanisms to respond to injury. Superficial injury heals via surface cells with histopathological changes like foveolar hyperplasia.
J. Goldenring, J. Mills
semanticscholar   +1 more source

Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia

Nature Cell Biology, 2021
The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one epithelial type is replaced by another.
Cindrilla Chumduri, Rajendra Kumar Gurumurthy, Hilmar Berger, O. Dietrich, Naveen Kumar, Stefanie Koster, V. Brinkmann, K. Hoffmann, M. Drabkina, Panagiota Arampatzi, Dajung Son, U. Klemm, H. Mollenkopf, H. Herbst, M. Mangler, J. Vogel, A. Saliba, T. Meyer   +17 more
semanticscholar   +1 more source

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

bioRxiv, 2021
BACKGROUND & AIMS Acinar to ductal metaplasia (ADM) occurs in the pancreas in response to tissue injury and is a potential precursor for adenocarcinoma.
Zhibo Ma, Nikki K. Lytle, Bob Chen, N. Jyotsana, S. Novak, Charles J. Cho, Leah R. Caplan, Olivia Ben-Levy, Abigail C. Neininger, D. Burnette, V. Trinh, M. Tan, Emilee A. Patterson, R. A. E. Drigo, Rajshekhar R. Giraddi, Cynthia Ramos, A. Means, I. Matsumoto, U. Manor, J. Mills, J. Goldenring, K. Lau, G. Wahl, Kathleen E. DelGiorno   +23 more
semanticscholar   +1 more source

The histologic spectrum of apocrine lesions of the breast [PDF]

Archive of Oncology, 2004
New data on apocrine carcinoma of the breast, especially on its unusual pathogenesis, are the facts that justify this study. The aim of this study was to describe the morphological features in both benign apocrine lesions and invasive apocrine carcinomas
Trenkić Srbobran, Katić Vuka V., Pashalina Mitsa, Živković Vesna V., Milentijević Maja, Kostov Miloš   +5 more
doaj   +1 more source

Identification of serum microRNAs as potential diagnostic biomarkers for detecting precancerous lesions of gastric cancer

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 63-70, January 2023., 2023
We found that microRNA‐196b‐5p was significantly upregulated in precancerous lesions and that combining it with other microRNAs increased the accuracy of detection. Since endoscopy is associated with risk, the identification of high‐risk groups for gastric cancer is expected to make it possible to clearly identify groups that should undergo endoscopy ...
Hajime Otsu, Sho Nambara, Qingjiang Hu, Yuichi Hisamatsu, Takeo Toshima, Kazuki Takeishi, Yusuke Yonemura, Takaaki Masuda, Eiji Oki, Koshi Mimori   +9 more
wiley   +1 more source

Premature Ejaculation – Dose and Duration Dependent Effect of Fluoxetine: A Histological Study on Seminal Vesicle of Albino Rats [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: Fluoxetine is a prototype drug of Selective Serotonin Reuptake Inhibitors. Its active demethylated metabolite has a half life of 7-10 d. Fluoxetine is used to treat depression and is also prescribed in premature ejaculation. Aim: In the
Alka Aggarwal, SL. Jethani, RK. Rohatagi, Juhi Kalra   +3 more
doaj   +1 more source

Apocrine metaplasia: a new type of müllerian metaplasia. [PDF]

Journal of Clinical Pathology, 1993
Apocrine differentiation was an incidental finding in an ovarian cyst. This is considered to be a further example of Müllerian metaplasia that has not been described before and which, theoretically, could occur in any organ of Müllerian derivation (ovary, uterus, cervix or fallopian tube).
C Allen, S Johnson
openaire   +3 more sources

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis

Human Mutation, Volume 43, Issue 12, Page 2091-2101, December 2022., 2022
Abstract The role of constitutional genetic defects in idiopathic pulmonary fibrosis (IPF) is increasingly appreciated. Monogenic disorders associated with IPF affect two pathways: telomere maintenance, accounting for approximately 10% of all patients with IPF, and surfactant biology, responsible for 1%–3% of cases and often co‐occurring with lung ...
Rachel M. Sutton, Humberto Trejo Bittar, Daniel I. Sullivan, Agustin Gil Silva, Harinath Bahudhanapati, Anishka H. Parikh, Yingze Zhang, Kevin Gibson, John F. McDyer, Daniel J. Kass, Jonathan K. Alder   +10 more
wiley   +1 more source

A case of carcinoma of the breast with metaplasia to chondrosarcoma: Light microscopic and immunohistochemical features [PDF]

Archive of Oncology, 2003
The breast carcinomas with metaplasia are rare neoplasms showing both carcinomatous and sarcomatous elements. We described clinical behavior radiology findings and pathological features in case of breast carcinoma with heterologous chondrosarcomatoid ...
Fenyvesi Attila
doaj   +1 more source