Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. [PDF]
, 2013 The phosphoinositide 3-kinase (PI3K) signaling cascade is a key mediator of cellular growth, survival and metabolism and is frequently subverted in human cancer.
Bentires-Alj, M +8 more
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대한영상의학회지, 2018 Metaplastic breast carcinoma is a rare type of neoplasms with mixed epithelial and mesenchymal differentiation. Metaplastic carcinoma with chondroid differentiation is relatively an uncommon type among the different types of metaplastic carcinoma.
Leehi Joo, Soo Hyun Yeo, Sun Young Kwon
doaj +1 more source
Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]
, 2010 Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte +63 more
core +6 more sources
Novel treatment for gastric intestinal metaplasia, a precursor to cancer
JGH Open, 2020 Background and Aim Gastric intestinal metaplasia (GIM) is precancerous with a worldwide prevalence of 25%. Eradicating Helicobacter pylori prevented about half of gastric cancers; failure to prevent the rest was attributed to GIM. GIM is irreversible and
Shiu Kum Lam, George Lau
doaj +1 more source
Local lung hypoxia determines epithelial fate decisions during alveolar regeneration. [PDF]
, 2017 After influenza infection, lineage-negative epithelial progenitors (LNEPs) exhibit a binary response to reconstitute epithelial barriers: activating a Notch-dependent ΔNp63/cytokeratin 5 (Krt5) remodelling program or differentiating into alveolar type II
Brumwell, Alexis N +13 more
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The gastric acid pocket is attenuated in H. pylori infected subjects [PDF]
, 2016 Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H.
Ballantyne, Stuart A. +6 more
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H. pylori-associated pathologic findings among Alaska native patients
International Journal of Circumpolar Health, 2018 Helicobacter pylori infection is common among Alaska native (AN) people, however scant gastric histopathologic data is available for this population. This study aimed to characterise gastric histopathology and H. pylori infection among AN people.
Leisha Diane Nolen +9 more
doaj +1 more source
New European guidelines for the management of patients with precancerous changes in the stomach
Медицинский совет, 2019 Aim of the review: to analyze the current aspects of the management of patients with precancerous changes in the stomach, as outlined in the new MAPS II European recommendations.Basic provisions.
V. V. Tsukanov +3 more
doaj +1 more source
Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig [PDF]
, 2018 Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ...
Hedley, J +4 more
core +2 more sources
Metaplastic Sarcomatoid Carcinoma of the Breast. Case Report
Medisur, 2018 Metaplastic Tumors of the mammary gland are infrequent. The diagnosis should be based on studies of hematoxylin and eosin, confirmed by inmunohistochemical markers.
Javier Martínez Navarro +3 more
doaj +2 more sources