Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte +63 more
core +6 more sources
Keratinizing squamous metaplasia of the upper urinary tract in a child with a solitary kidney
We report a rare case of keratinizing squamous metaplasia of the upper urinary tract in a child with a single kidney. Squamous metaplasia has rarely been reported in the upper urinary tract, and is even rarer in children.
Prashant Jain +2 more
doaj +1 more source
The gastric acid pocket is attenuated in H. pylori infected subjects [PDF]
Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H.
Ballantyne, Stuart A. +6 more
core +1 more source
Chronic inflammation of the gastric mucosa, often caused by autoimmune gastritis and/or infection with Helicobacter pylori, can lead to atrophy of acid‐secreting parietal cells with metaplasia of remaining cells. The histological pattern marks a critical
L. Osaki +6 more
semanticscholar +1 more source
Metaplastic breast carcinoma is a rare type of neoplasms with mixed epithelial and mesenchymal differentiation. Metaplastic carcinoma with chondroid differentiation is relatively an uncommon type among the different types of metaplastic carcinoma.
Leehi Joo, Soo Hyun Yeo, Sun Young Kwon
doaj +1 more source
Intestinal Metaplasia of the Stomach
AbstractIntestinal metaplasia (IM) of the stomach is associated with a very small increased risk of developing gastric cancer. Endoscopic surveillance has been proposed and advocated for populations at risk. Risk factors for IM include Helicobacter pylori infection, high salt intake, smoking, alcohol consumption, and chronic bile reflux.
Ruonan Wu, S-J Tang, F Bhaijee
openaire +2 more sources
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model. [PDF]
Pancreatic duct glands (PDGs) have been hypothesized to give rise to pancreatic intraepithelial neoplasia (PanIN). Treatment with the glucagon-like peptide (GLP)-1 analog, exendin-4, for 12 weeks induced the expansion of PDGs with mucinous metaplasia and
Butler, Peter C +5 more
core +1 more source
Novel treatment for gastric intestinal metaplasia, a precursor to cancer
Background and Aim Gastric intestinal metaplasia (GIM) is precancerous with a worldwide prevalence of 25%. Eradicating Helicobacter pylori prevented about half of gastric cancers; failure to prevent the rest was attributed to GIM. GIM is irreversible and
Shiu Kum Lam, George Lau
doaj +1 more source
Minor Salivary Gland Changes in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma - A Histopathological Study [PDF]
Introduction: The most common etiology for Oral Squamous Cell Carcinoma (OSCC) is tobacco and tobacco related products which cause nuclear damage to the keratinocytes.
SUNIL PARAMEL MOHAN +5 more
doaj +1 more source
Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis : 48-week results from the EMBARK study [PDF]
Objective: To evaluate the efficacy and safety of etanercept (ETN) after 48 weeks in patients with early active non-radiographic axial spondyloarthritis (nr-axSpA).
Bonin, Randi +15 more
core +1 more source

