Results 71 to 80 of about 100,911 (305)

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

Exploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu, Junya Feng, Jie Ma, Tixian Xiao, Wei Yuan   +4 more
wiley   +1 more source

Dedifferentiation of esophageal progenitors in metaplasia and cancer

Molecular & Cellular Oncology, 2021
Barrett syndrome is a squamo-columnar metaplasia increasing the risk of developing esophageal adenocarcinoma. Recently, we showed that esophageal cells can transdifferentiate into undifferentiated columnar cells in vivo.
Alizée Vercauteren Drubbel, Benjamin Beck   +1 more
doaj   +1 more source

Expression of MUC-2, MUC-6, NAPE-PLD, IL-6 and IL-13 in Healthy and Metaplastic Bronchial Epithelium

Diseases, 2022
Background: The normal tissue structure of the respiratory system is necessary to provide adequate protection of the airways and lungs. Prolonged exposure to trigger factors can result in adaptive mechanism activation and lead to the development of ...
Elizabeta Lohova, Mara Pilmane
doaj   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Cirurgias conservadoras do baço para tratamento da esplenomegalia por mielofibrose

Revista Brasileira de Hematologia e Hemoterapia, 2002
A mielofibrose idiopática é uma doença mieloproliferativa crônica, que pode evoluir com hepatoesplenomegalia, também denominada metaplasia, e acometer vários órgãos. Ocasionalmente, o baço alcança proporções gigantescas e precisa ser retirado. Entretanto,
Andy Petroianu
doaj   +1 more source

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]

, 2008
<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Derakhshan, M.H., Didevar, R., Fyfe, V., Kazemi, A., Malekzadeh, R., McColl, K.E.L., Rakhshani, N., Sotoudeh, M., Watabe, H., Yazdanbod, A., Zolfeghari, A.   +10 more
core   +1 more source

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [PDF]

, 2014
Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc).
Baffa, R, Bornschein, J, Braconi, C, Croce, CM, D'Angelo, E, Dall'Olmo, L, Fassan, M, Galasso, M, Gasparini, P, Nuovo, GJ, Pizzi, M, Realdon, S, Rugge, M, Souza, RF, Valeri, N, Vicentini, C, Volinia, S, Zaninotto, G   +17 more
core   +4 more sources

Myeloid metaplasia of the breast

Annals of Oncology, 2001
Hereby, we present the case of a 50-year-old woman with 5-year history of chronic idiopathic myelofibrosis who was referred to our institution after she had noted a lump in the breast. Histological examination of the lesion removed from her left breast yielded the diagnosis of extramedullary hematopoiesis in the breast.
M. Bracko, T. Cufer
openaire   +3 more sources

Single‐cell sequencing reveals the role of IL‐33+ endothelial subsets in promoting early gastric cancer progression

iMeta, EarlyView.
A single‐cell atlas was established to reveal the molecular characteristics of early gastric cancer (EGC). In combination with organoids, animal models, and clinical samples, it was found that subpopulations such as pit mucous‐like cell (PMC‐like), proliferating cell (PC), CH25H+ CD4+ T cell, IL‐33+ endothelial cell, and ADAMTSL2+ endothelial cell are ...
Li Zhou, Mei Yang, Chao Deng, Manqiu Hu, Suhua Wu, Kewen Lai, Lili Zhang, Zhiji Chen, Qin Tang, Qingliang Wang, Lu Chen, Runmin Zha, Yuanyuan Chen, Yibo Tan, Song He, Zhihang Zhou   +15 more
wiley   +1 more source

Metaplastic Sarcomatoid Carcinoma of the Breast. Case Report

Medisur, 2018
Metaplastic Tumors of the mammary gland are infrequent. The diagnosis should be based on studies of hematoxylin and eosin, confirmed by inmunohistochemical markers.
Javier Martínez Navarro, Martha Yudey Rodríguez Pino, Virgen Yasmín Rodríguez Navarro, Lisanka Fumero Roldán   +3 more
doaj   +2 more sources