Results 61 to 70 of about 135,944 (307)

Meta-SQL: Towards Practical Meta-Querying [PDF]

open access: yes, 2004
Enterprise databases often contain not only ordinary data, but also queries. Examples are view definitions in the system catalog; usage logs or workloads; and stored procedures as in SQL/PSM or Postgres. Unfortunately, these queries are typically stored as long strings, which makes it hard to use standard SQL to express meta-queries: queries about ...
Jan Van den Bussche   +2 more
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Política macroeconômica do governo Lula: uma crítica pós-Keynesiana [PDF]

open access: yes, 2010
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O presente trabalho tem como tema central a política macroeconômica do governo Lula, a qual foi fundamentada nos pilares teóricos daquilo que tradicionalmente é ...
Araújo, Assilio Luiz Zanella de
core  

Notificación de agresiones por los trabajadores del Servicio Madrileño de Salud

open access: yes, 2023
Objective: to understand the prevalence of aggressions reported by the Madrid Health Service staff, to learn about the prevalence of lesions or health alterations caused to workers for this reason, and to identify the factors associated with said ...
Solís-Muñoz, Montserrat   +6 more
core   +1 more source

Metodología de evaluación ex post

open access: yesPensamiento Crítico, 2010
El presente artículo ofrece una síntesis de la metodología de evaluación ex post empleada por el autor en la evaluación del II Programa de Inversiones Sociales y de Infraestructura contra la Pobreza (en adelante, el Programa), ejecutado por el MEF, con ...
David Medianero Burga
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A privatização da telefonia fixa: um estudo sobre os impactos em Santa Catarina [PDF]

open access: yes, 2008
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.Este trabalho tem especial objetivo de descrever o modelo de regulação aplicado às telecomunicações no Brasil, focalizando particularmente o caso da telefonia fixa.
Bernardo, Hamilton
core  

As influências na motivação para o trabalho em ambientes com metas e recompensas: um estudo no setor público

open access: yesRevista de Administração Pública, 2014
Este estudo investigou as influências na motivação para o trabalho apoiando-se nas teorias de Latham e Locke (2002), Porter e Lawler III (1968), Vroom (1964) e Wright (2001, 2007).
Weslei Alves Rodrigues   +2 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

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