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A Window into Metastasis [PDF]

open access: possibleScience Translational Medicine, 2012
A glass window constructed by Ritsma, Steller et al. (this issue) allows chronic, high-resolution imaging of metastasis in the mouse abdomen.
Jochen Herms   +2 more
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Metastasis of chondrosarcoma

Journal of Cancer Research and Clinical Oncology, 1996
This study was undertaken to analyse metastases of patients with intermediate- or high-grade chondrosarcomas. Out of 24 intermediate-grade tumours, 5 (21%) developed metastases, as did 6 of 10 high-grade tumors (60%) (P = 0.04). Four patients developed pulmonary metastasis only, 5 developed both pulmonary metastasis and metastases of the other sites ...
Toshifumi Ozaki   +4 more
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Leptomeningeal metastasis

Current Opinion in Oncology, 2009
Leptomeningeal metastasis occurs in ~5% of all patients with cancer and is the third most common metastatic complication of the central nervous system. Staging of leptomeningeal metastasis includes contrast-enhanced brain and spine magnetic resonance imaging and radionuclide cerebrospinal fluid (CSF) flow study.
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A Normative Metastasis?

SSRN Electronic Journal, 2020
The article presents the argument that contemporary societies are facing an ever-growing over-production of norms which are chocking its efficient functioning. The argument however is subsequently de-constructed, in particular through a comparative (European vs.
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Biology of metastasis

Cancer, 1986
The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression.
Isaiah J. Fidler, Philip Frost
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Planting metastasis early

Nature Reviews Cancer, 2017
Two papers demonstrate that early disseminated cancer cells (DCCs) from HER2+breast cancer are more likely to seed metastasis than those from established tumours.
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Metastasis of metastases

The American Journal of Surgery, 1975
Metastasis of metastases was demonstrated experimentally. Mice whose primary tumors were amputated after the development of pulmonary metastases were placed into parabiosis with normal syngeneic partners. Metastases were demonstrated in the nontumor-bearing partners despite their development of passive immunity.
Herbert C. Hoover, Alfred S. Ketcham
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Treatment of Metastasis

Veterinary Clinics of North America: Small Animal Practice, 1985
Metastasis is the major cause of death in human cancer patients. Understanding the pathogenesis of metastasis will improve the treatment and prognosis of cancer.
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Mechanisms of Metastasis

Clinical Orthopaedics and Related Research, 1982
The mechanism by which a malignant tumor cell establishes a metastatic foci is a complex process requiring the successful completion of a series of steps. If any step cannot be completed, the entire process fails. The tumor cell must separate from the primary tumor, gain access to an efferent channel (lymphatic or vascular), survive transport to a ...
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Vertebroplasty for Metastasis [PDF]

open access: possibleMedical Oncology, 2003
Vertebral metastases are frequently asymptomatic; however, the occurrence of a pathological (micro-)fracture may be associated with unremitting pain, instability, and even kyphoscoliotic deformity and require prompt and effective treatment. In symptomatic patients, the beneficial effect of conservative therapies requires too much time.
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