Results 31 to 40 of about 336,084 (346)

Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma. [PDF]

, 2016
Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC
Arron, Sarah, Chang, Anne, Day, Bann-Mo, Lewis, Karl, McKenna, Edward, Migden, Michael, Sekulic, Aleksandar, Solomon, James, Yoo, Simon   +8 more
core   +2 more sources

A lobulated mass on the upper back with prominent vasculature: A giant basal cell carcinoma

Dermatology Reports, 2021
Basal cell carcinoma (BCC) is characterized by slow but locally invasive growth. Although there is low metastatic potential, if not treated early, these skin cancers can lead to significant morbidity and mortality.
Elysha M. Kolitz, Brian L. Scott , Travis Vandergriff, Melissa Mauskar   +3 more
doaj   +1 more source

Histology of non-melanoma skin cancers. An Update [PDF]

, 2017
Non-melanoma skin cancer (NMSC) is the most frequently diagnosed cancer in humans. Several different non-melanoma skin cancers have been reported in the literature, with several histologic variants that frequently cause important differential diagnoses ...
Cantisani, Carmen, Didona, Dario, Donati, Michele, Mercuri, Santo Raffaele, Paolino, Giovanni   +4 more
core   +2 more sources

Eccrine porocarcinoma of the head: An important differential diagnosis in the elderly patient [PDF]

, 2008
Background: Eccrine porocarcinoma is a rare malignant tumor of the sweat gland, characterized by a broad spectrum of clinicopathologic presentations. Surprisingly, unlike its benign counterpart eccrine poroma, eccrine porocarcinoma is seldom found in ...
Akiyoshi E, Brenn T, Cho SB, Daniela Bruch-Gerharz, Dummer R, Goel R, Grimme H, Gunhan, Gutermuth J, Helmke B, Klaus-Werner Schulte, Lan CC, Matloub HS, Mishima Y, Perna C, Peter Arne Gerber, Pinkus H, Plunkett TA, Puttick L, Ritter AM, Robson A, Shaw M, Sigal R, Thomas Ruzicka, Valverde K, Wittenberg GP   +25 more
core   +1 more source

Hedgehog Pathway Inhibitor Therapy for Locally Advanced and Metastatic Basal Cell Carcinoma: A Systematic Review and Pooled Analysis of Interventional Studies.

JAMA dermatology, 2016
IMPORTANCE Hedgehog pathway inhibitors (HPIs) were made available by US Food and Drug Administration approval in 2012 for vismodegib and 2015 for sonidegib.
A. Jacobsen, A. Aldahan, O. Hughes, Vidhi V. Shah, J. Strasswimmer   +4 more
semanticscholar   +1 more source

The molecular basis for ethnic variation and histological subtype differences in prostate cancer. [PDF]

, 2013
Prostate cancer is a common malignancy among men in Western countries. Recently the morbidity and mortality of prostate cancer increase dramatically in several oriental countries including China.
Goldstein, Andrew S, Huang, Jiaoti, Zong, Yang   +2 more
core   +1 more source

Basal cell carcinoma: PD-L1/PD-1 checkpoint expression and tumor regression after PD-1 blockade

Journal for ImmunoTherapy of Cancer, 2017
Monoclonal antibodies that block immune regulatory proteins such as programmed death-1 (PD-1) have demonstrated remarkable efficacy in controlling the growth of multiple tumor types.
Megan Schollenberger, Evan Lipson, William H. Sharfman, Janis M. Taube, Haiying Xu, Aleksandra Ogurtsova, Jessica Esandrio, Mohammed T. Lilo, Patricia Brothers   +8 more
doaj   +1 more source

Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]

, 2015
Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina, FRAMARINO DEI MALATESTA, Marialuisa, Iannini, Isabella, Masselli, Gabriele, Pecorella, Irene, Sammartino, Paolo   +5 more
core   +2 more sources

Sphingosine kinase 1 in breast cancer: A new molecular marker and a therapy target [PDF]

, 2020
It is now well-established that sphingosine kinase 1 (SK1) plays a significant role in breast cancer development, progression, and spread, whereas SK1 knockdown can reverse these processes.
Alshaker, Heba, Pchejetski, Dmitri, Thrower, Hannah   +2 more
core   +1 more source

Androgen receptors beyond prostate cancer: an old marker as a new target. [PDF]

, 2014
Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary effects in this malignancy.
Kurzrock, Razelle, Munoz, Javier, Wheler, Jennifer J   +2 more
core   +2 more sources