Results 51 to 60 of about 7,302 (186)

Multi‐Level Genomic and Computational Analyses Identify a Novel IFT122 Variant Associated With Cranioectodermal Dysplasia 1 in a Consanguineous Saudi Family

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Integrated phenotypic, genomic and computational analyses identified a novel homozygous IFT122 variant causing cranioectodermal dysplasia 1. Structural modeling predicts destabilization of IFT122 protein and altered interactions within the IFT‐A complex, supporting its pathogenicity.
Deema Aljeaid, Abdulrahman Almadiny, Khalidah K. Nasser, Mahmoud Almutadares, Noha M. Issa   +4 more
wiley   +1 more source

Key concepts in children's footwear research: a scoping review focusing on therapeutic footwear

Journal of Foot and Ankle Research, Volume 12, Issue 1, 2019., 2019
Abstract Background Reports suggest that children with mobility impairment represent a significant proportion of the population living with a disability. Footwear is considered to be the key extrinsic factor affecting children's gait and footwear modifications have been historically postulated to assist with locomotory difficulty.
Matthew Hill, Aoife Healy, Nachiappan Chockalingam   +2 more
wiley   +1 more source

Combined Cuboid-Cuneiform Osteotomy For Correction Of Residual Forefoot Adduction Deformity In Idiopathic Clubfoot [PDF]

Zagazig University Medical Journal
Background: Residual forefoot adduction deformity refers to the persistent inward deviation of the forefoot in patients following corrective procedures for idiopathic clubfoot, with reported incidence rates varying up to 95%.
Mohamed Mady, Riad Megahed, Sami Ali, Mohamed El-Hefnawy   +3 more
doaj   +1 more source

Can Prenatal Ultrasound and Genetic Testing Reliably Exclude Non‐Isolated Clubfoot?

Prenatal Diagnosis, Volume 46, Issue 1, Page 30-38, January 2026.
ABSTRACT Objective The aim of this study is to evaluate the efficacy of prenatal second trimester ultrasound in diagnosing isolated congenital clubfoot and to assess the role of prenatal genetic testing. Methods We conducted a retrospective cohort study in the North‐West region of the Netherlands with prenatally suspected clubfoot between 16 and 24 ...
Jana M. de Vries, Arda Arduc, Elisabeth van Leeuwen, Maria B. Tan – Sindhunata, Peter Struijs, Melinda Witbreuk, Ingeborg H. Linskens, Eva Pajkrt   +7 more
wiley   +1 more source

The “AdductoValgus” Foot: Description of Deformity and Technique for Surgical Reconstruction

Foot & Ankle Orthopaedics, 2019
Category: Midfoot/Forefoot Introduction/Purpose: The literature is replete with descriptions of metatarsus adductus (pediatric patients) and metatarsus primus varus (adult patients) deformities along with recommendations for treatment.
Robert R. Gorman MD
doaj   +1 more source

The Relationship Between Developmental Dysplasia of the Hip (DDH) and Congenital Talipes Equinovarus (CTEV)—A Retrospective Case Series

Journal of Paediatrics and Child Health, Volume 61, Issue 7, Page 1116-1121, July 2025.
ABSTRACT Backgrounds There is no consensus if a relationship exists between idiopathic congenital talipes equinovarus (CTEV) and developmental dysplasia of the hip (DDH). Our research aim was to provide a contemporary Australian population statistical relationship between DDH and idiopathic CTEV, compared to published data.
Andrew Gorrie, Natalie Tannos, Dean Morris, Andrew Leicester, Jeffrey S. Ling, Arnold Suzuki, Samya Lakis   +6 more
wiley   +1 more source

Determining the clinical knowledge and practice of Australian podiatrists on children with developmental coordination disorder: a cross‐sectional survey

Journal of Foot and Ankle Research, Volume 12, Issue 1, 2019., 2019
Abstract Background Developmental coordination disorder (DCD) is a common condition in children affecting motor coordination. This impacts on academic performance, and activities of daily living. Literature surrounding interventions for DCD has focused mostly on physical and occupational therapies. However, it is known that children with DCD present to
Mitchell Smith, Helen A. Banwell, Emily Ward, Cylie M. Williams   +3 more
wiley   +1 more source

Management of Patella Dislocation in Say‐Barber‐Biesecker‐Young‐Simpson’s Syndrome: A Report of Two Cases

Case Reports in Orthopedics, Volume 2018, Issue 1, 2018., 2018
Say‐Barber‐Biesecker‐Young‐Simpson’s syndrome is one of the Ohdo‐like syndromes. It is a very rare congenital condition that is commonly defined by its main clinical features that are blepharophimosis, ptosis, mental retardation, and delayed motor development. They are often associated with skeletal manifestations that are joint laxity, long thumbs and
Meni Mundama, Serge Ayong, Renaud Rossillon, Athanassios Papanikolaou   +3 more
wiley   +1 more source

Unraveling the Genetic Landscape of Foot Arch Morphology: A Systematic Review of Single Nucleotide Polymorphisms

Clinical Genetics, Volume 107, Issue 5, Page 485-494, May 2025.
This systematic review identifies 137 SNPs linked to genetic disorders affecting foot morphology but finds no direct studies on common foot arch variations. The findings highlight a research gap and emphasize the need for large‐scale genetic studies to distinguish between natural variations and pathology‐driven foot deformities.
Yukun He, Marlies Verleyen, Bert Callewaert, Arne Burssens, Emmanuel Audenaert   +4 more
wiley   +1 more source

Refinement of Modified Endoscopic Lateral Soft‐Tissue Procedure for Correction of Hallux Valgus Deformity

Arthroscopy Techniques, Volume 14, Issue 3, March 2025.
Abstract Hallux valgus is a common orthopaedic problem, and surgical correction frequently is indicated for symptomatic deformity. The modified endoscopic distal soft‐tissue procedure has been reported to provide a minimally invasive approach of hallux valgus correction with augmentation of the medial metatarsosesamoid suspensory ligament and ...
Tun Hing Lui, Charles Churk Hang Li, Amanda Mun Yee Slocum, Siu Kei Kam   +3 more
wiley   +1 more source