Results 161 to 170 of about 21,871,524 (296)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Microbiological Quality and Safety of Fresh Turkey Meat at Retail Level, Including the Presence of ESBL-Producing Enterobacteriaceae and Methicillin-Resistant S. aureus. [PDF]

Foods, 2023
Martínez-Laorden A, Arraiz-Fernández C, González-Fandos E.   +2 more
europepmc   +1 more source

Long‐Term Outcomes of Sacral Neuromodulation Explantation: A 12‐Year Experience at a High‐Volume Tertiary Center

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacral neuromodulation (SNM) is a therapeutic option offered to patients with idiopathic overactive bladder (OAB) or non‐obstructive urinary retention, as an alternative treatment for refractory medical management. It allows for electrical stimulation of inhibitory circuits that modulate the micturition reflex and improve lower ...
Carly Fiorido, Mario Henrique Bitar Siqueira, Mohammed Aldoukhi, Nojoud Alamri, Eviatar Fields, Naeem Bhojani, Bilal Chughtai, Omar Buksh, Sagi Shprits, Katherine Lajkosz, Dean Elterman   +10 more
wiley   +1 more source

Cas12a/Guide RNA-Based Platforms for Rapidly and Accurately Identifying <i>Staphylococcus aureus</i> and Methicillin-Resistant <i>S. aureus</i>. [PDF]

Microbiol Spectr, 2023
Cao X, Chang Y, Tao C, Chen S, Lin Q, Ling C, Huang S, Zhang H.   +7 more
europepmc   +1 more source

Umbrella Review for Pediatric Sepsis and Robust Prediction Potential Worldwide

Pediatric Discovery, EarlyView.
ABSTRACT Pediatric sepsis remains a significant global health burden with considerable mortality and morbidity, particularly in resource‐limited settings. This umbrella review synthesizes current evidence from systematic reviews and meta‐analyses on the definitions, epidemiology, diagnostic approaches, prognostic models, and emerging prediction ...
Wenbo Fu, Yumei Li, Kee Chong Ng, Sheng Fu   +3 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

In Vitro Activity of Bacteriophages Against Ocular Methicillin-resistant S. aureus Isolates Collected in the US. [PDF]

Ophthalmol Ther
André C, Medina M, Kolenda C, Blazière L, Helluin E, Resch G, Bispo PJM, Laurent F.   +7 more
europepmc   +1 more source

Naphthoquinone-derivative as a synthetic compound to overcome the antibiotic resistance of methicillin-resistant S. aureus. [PDF]

Commun Biol, 2020
Song R, Yu B, Friedrich D, Li J, Shen H, Krautscheid H, Huang SD, Kim MH.   +7 more
europepmc   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source