Results 161 to 170 of about 180,876 (291)

Multivalent Glycopolymer Design Unlocks Antimicrobial Activity of 2‐Deoxyglucose

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
New approaches to combat antimicrobial‐resistant pathogens are needed. Here, scaffolding a nonmetabolizable sugar (2DG) on a polymer backbone is shown to significantly improve its antimicrobial activity. ABSTRACT With the increasing prevalence of multidrug‐resistant (MDR) pathogens, last‐line therapeutics such as cyclic peptides are insufficient ...
Sungjin Jeon, Xianjin Qin, Marjon Zamani, Ariel L. Furst, Cassandra E. Callmann   +4 more
wiley   +2 more sources

Prevalence and genetic characterization of methicillin-resistant Staphylococcus aureus in Commercial aquaculture farms in Egypt. [PDF]

Sci Rep
El-Ashker M, Monecke S, Gwida M, Rezk M, Müller E, Saad T, Akinduti P, Ehricht R.   +7 more
europepmc   +1 more source

Antimicrobial Secondary Metabolites From Rhizosphere‐Associated Streptomyces Species in Northern Nigerian Agricultural Soils: Genomic Mining and Bioactivity Assessment

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Nigerian agricultural soils harbour diverse Streptomyces species producing novel antimicrobial secondary metabolites. Genomic mining revealed 187 biosynthetic gene clusters, leading to isolation of twelve new compounds with potent activity against multidrug‐resistant pathogens, including MRSA and vancomycin‐resistant Enterococcus. ABSTRACT Streptomyces
David Adeiza Zakari, Sarafadeen Olateju Kareem, Obuotor Tolulope Mobolaji, Akinloye Oluseyi Adeboye, Adefila Moyosore Adebimpe   +4 more
wiley   +1 more source

Pathoadaptive evolution and clonal dissemination of community- associated methicillin-resistant Staphylococcus aureus in Egypt. [PDF]

BMC Infect Dis
Saif NA, Elghaish RA, Badr E, Mouftah SF, Shawky SM, Pascoe B, Sheppard SK, Elhadidy M.   +7 more
europepmc   +1 more source

Tissue‐retained needles in people who inject drugs: A systematic review of case reports and series on clinical presentations, complications and management

Addiction, Volume 121, Issue 6, Page 1381-1397, June 2026.
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala, Anna Nevalainen, Irina Rinta‐Kiikka, Samuel Heikkilä, Sisu Kiuru, Markku Sumanen, Otso Arponen, Olli Nevalainen   +7 more
wiley   +1 more source

Panton-Valentine Leukocidin-Encoding Methicillin-Resistant Staphylococcus aureus, the Netherlands, 2023-2024¹. [PDF]

Emerg Infect Dis
van Schelven P, Nijhuis R, Jamin C, Goemans S, Hintaran P, van der Jagt-Zwetsloot M, Smilde A, Ter Horst A, de Graaf M, Notermans DW, Russcher A, Raven S.   +11 more
europepmc   +1 more source

A Transdisciplinary Allied Health “Flying Squad” to Overcome Non‐Medical Barriers to Discharge From Hospital: A Feasibility Study

Journal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Rationale Acutely hospitalised patients may be medically ready for discharge but face psychosocial and other non‐medical barriers to returning home. This increases their length of stay and may lead to exposure to hospital associated risks such as hospital‐acquired infections.
Aruska N. D'Souza, James Fitzpatrick, Kate Palmer, Hana McDonald, Jane Jolley, Genevieve Juj, Casey L. Peiris   +6 more
wiley   +1 more source

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

Veterinary Dermatology, Volume 37, Issue 3, Page 427-436, June 2026.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron, Darko Stefanovski, Youwen You, Rachel Proctor, Donna Watson, Julie Randall, Christine L. Cain   +6 more
wiley   +1 more source

Oritavancin as rescue therapy in severe methicillin-resistant Staphylococcus aureus pneumonia: A case report. [PDF]

Respir Med Case Rep
Virzì F, Giacopelli G, Tutone P, Tomasello S.   +3 more
europepmc   +1 more source

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
Ruthenium(II) (Ru(II)) pyrazolyl–pyridine half‐sandwich complexes (C1–C6) were synthesized and structurally characterized as prospective metalloantibiotics. Screening through the Community for Open Antimicrobial Drug Discovery (CO‐ADD) revealed selective activity against Acinetobacter baumannii, with favorable cytotoxicity profiles. Biophysical studies
M. Cassiem Joseph, Sheldon Sookai, Monika Nowakowska, Rotondwa Mphephu, Angela M. Kavanagh, Johannes Zuegg, Mark A. T. Blaskovich, Andrew J. Swarts   +7 more
wiley   +1 more source