Results 211 to 220 of about 111,670 (292)

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová, Šárka Štěpánková, Eva Frýbová, Klára Konečná, Jana Korbielová, Markéta Švarcová, Ondřej Janďourek, Václav Pflégr, Szilvia Bősze, Martin Krátký   +9 more
wiley   +1 more source

Citrus reticulata Blanco: A Review on Chemical Composition and Biological Activities

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
This review compiles chemical information and biological activities from 49 studies on Citrus reticulata. The fruit peels stand out for their high content of methoxylated monoterpenes and flavonoids with antioxidant, anti‐inflammatory, and antimicrobial activities.
José Walber Gonçalves Castro, Geane Gabriele de Oliveira Souza, José Galberto Martins da Costa, Fabíola Fernandes Galvão Rodrigues   +3 more
wiley   +1 more source

Synthesis of 2‐(Quinoxalin‐2‐yl)acetamides and Their Preliminary Cytotoxic and Antibacterial Activity

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Quinoxaline is an aza‐heterocycle found in some bioactive compounds. Thus, to enhance the pharmacological scope of this nucleus, we report a series of 19 acetamides decorated with a quinoxaline core. The synthesis involved the linkage of previously constructed bromoacetamides and hydroxyphenyl quinoxalines via an SN2 reaction. The first series
Cesar E. Tovar‐Roman, Eduardo Hernández‐Vázquez, José A. Rivera‐Chávez   +2 more
wiley   +1 more source

Molecular epidemiology and geographical variation of methicillin-resistant Staphylococcus aureus: a multicentre study across Xinjiang, China. [PDF]

BMC Microbiol
Shi Q, Zha H, Wang H, Song Y, Wang L, He L, Yan J, Deng Z, Zhang X.   +8 more
europepmc   +1 more source

Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities

ChemBioChem, Volume 27, Issue 1, January 2026.
A biochemical characterization of Staphylococcus aureus serine proteases SplA and SplB allelic variants (recombinantly produced in E. coli and purified) reveals that allelic variation adds an extra layer of complexity to the functioning of virulence factors in S. aureus colonization and infection.
Felix L. Glinka, Katharina Mehnert, Lena Koch, Ole Schmöker, Leif Steil, Christian Hentschker, Uwe Völker, Thor B. Johannesen, Dominique Böttcher, Michael Lammers, Barbara M. Bröker, Uwe T. Bornscheuer   +11 more
wiley   +1 more source

Early-Onset Methicillin-Resistant Staphylococcus aureus Blebitis Following PRESERFLO™ MicroShunt Implantation: A Case Report. [PDF]

Cureus
Mieno H, Ueno M, Sotozono C.
europepmc   +1 more source

Third‐Degree Burns of the Upper Aerodigestive Tract Caused by a Flare Gun: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Flare gun‐related injuries of the upper aerodigestive tract are extremely rare and can result in life‐threatening third‐degree burns with deep thermal damage and foreign body complications. Early recognition and multidisciplinary care are crucial, yet prognosis remains poor, underscoring the need for awareness of this devastating injury ...
Lukas Schmutzler, Matthias Santer, Johanna Leitgeb, Benedikt Hofauer, Daniel Dejaco   +4 more
wiley   +1 more source

Enhancing Surgical Decision‐Making for Infected Cardiac Device Lead Removal With 18F‐FDG PET/CT: A Case Study and Literature Analysis

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Residual implantable cardiac electronic device (ICED) leads pose a significant infection risk, necessitating a multimodal diagnostic and therapeutic approach. This case highlights the critical role of PET/CT imaging in guiding surgical decision‐making, particularly in cases of chronic infections with embedded or fractured lead fragments. While
Said Khallikane, Reda Mounir, Noureddine Atmani, Abdessamad Abdou, Ayoub Belhadj, Younes Aissaoui   +5 more
wiley   +1 more source

In Vivo Emergence of Oxacillin Resistance in mecA‐Negative MSSA Endocarditis With Metastatic Infection

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Staphylococcus aureus bacteremia (SAB) is particularly challenging when complicated by infective endocarditis (IE), metastatic spread, or evolving antimicrobial resistance. We describe a 76‐year‐old woman with poorly‐controlled diabetes who presented with bilateral knee septic arthritis and persistent methicillin‐sensitive S.
Leandro Bosch, Alexie Carletti, Toluwalase Awoyemi, Mohamed Al‐Kazaz, Alexander J. Nemeth, David Young   +5 more
wiley   +1 more source