Results 121 to 130 of about 128,189 (324)

Phenotypic and Genotypic Characterization of Macrolide, Lincosamide and Streptogramin B Resistance among Clinical Methicillin-Resistant Staphylococcus aureus Isolates in Chile [PDF]

, 2022
Mario Quezada-Aguiluz, Alejandro Aguayo-Reyes, Cinthia Carrasco, Daniela Mejías, Pamela Alejandra Escalante Saavedra, Sergio Mella-Montecinos, Andrés Opazo-Capurro, Helia Bello‐Toledo, José M. Munita, Juan Carlos Hormazábal, Gerardo González‐Rocha   +10 more
openalex   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance [PDF]

, 2018
Donghui Choe, Richard Szubin, Samira Dahesh, Suhyung Cho, Victor Nizet, Bernhard Ø. Palsson, Byung‐Kwan Cho   +6 more
openalex   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

Detection of Methicillin-Resistance Gene (mec-A) in Staphylococcus aureus Strains by PCR and Determination of Antibiotic Sensitivity

پزشکی بالینی ابن سینا, 2007
Background & Objective: Methicillin–Resistant Staphylococcus aureus (MRSA) is one of the most important causes of hospital infections worldwide. Treatment of these infections has become more difficult because of resistance to methicillin/oxacillin and ...
Alireza Zamani, Siavash Sadeghian, Mohammad Najafi Mosleh, Mohammad Taghi Goodarzi, Rasoul Yousefi Mashouf, Jalal Ghaderkhani   +5 more
doaj  

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

BMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui, Lu Zhang, Junyi Li, Yue Chen, Sheng Dai, Manfred F. Maitz, Ansha Zhao, Ping Yang   +7 more
wiley   +1 more source

A pH‐responsive charge‐reversal liposome with enhanced biofilm penetration for multimodal synergistic therapy of bacterial infections

BMEMat, EarlyView.
This study develops a pH‐responsive, charge‐reversal liposome for treating bacterial biofilm infections. With enhanced penetration capability, the liposome effectively delivers antibacterial agents into biofilms. By integrating photodynamic and photothermal therapies with antibiotics, it significantly eradicates biofilms and accelerates bacteria ...
Ruyue Li, Bo Liu, Cheng Wang, Zhencheng Sun, Shuyi Lv, Liang Tian, Minghui Xiao, Qinyang Zheng, Linqi Shi, Chunlei Zhu   +9 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

Chemistry &Biodiversity, EarlyView.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva, Nara juliana Santos Araujo, Cícera Datiane Morais Oliveira‐Tintino, José Maria Barbosa Filho, Gabriel Gonçalves Alencar, José Bezerra de Araújo‐Neto, Josefa Sayonara dos Santos, Juliete Bezerra Soares, Carolina Bandeira Domiciano, Henrique Douglas Melo Coutinho, Jacqueline Cosmo Andrade‐Pinheiro   +10 more
wiley   +1 more source

Methicillin Resistance Increased the Risk of Treatment Failure in Native Joint Septic Arthritis Caused by Staphylococcus aureus. [PDF]

Antibiotics (Basel), 2023
Kim J, Park SY, Sohn KM, Kim B, Joo EJ.
europepmc   +1 more source